2-T-BUTYLTHIOPHENE Chemical Properties

Melting point:

-59.1°C

Boiling point:

163.95°C

Density 

0.9967 (estimate)

refractive index 

1.5197 (estimate)

storage temp. 

2-8°C(protect from light)

solubility 

Chloroform, Methanol (Slightly)

form 

Oil

color 

Colourless

LogP

3.558 (est)

EPA Substance Registry System

2-tert-Butylthiophene (1689-78-7)

2-T-BUTYLTHIOPHENE Usage And Synthesis

Synthesis

A dichloromethane (30 mL) solution of thiophene (12.0 g, 0.143 mol) and bromo-tert-butane (19.6 g, 0.143 mol) was slowly added dropwise to a suspension of dichloromethane (30 mL) containing aluminum trichloride (19.1 g, 0.143 mol) at -78 °C for a controlled period of 1 hour. The reaction mixture was stirred continuously at -78 °C for 2 hours, followed by slow warming to room temperature and continued stirring for 18 hours. Upon completion of the reaction, the reaction mixture was diluted with dichloromethane and washed sequentially with water, 5% sodium hydroxide solution and water. The organic layer was dried with anhydrous sodium sulfate, filtered and concentrated under reduced pressure to remove the solvent to give the crude product. The crude product was purified by vacuum distillation (20 mmHg) to give 10.7 g of 2-(tert-butyl)thiophene in 53% yield.

References

[1] Patent: US2004/10013, 2004, A1. Location in patent: Page/Page column 65

2-T-BUTYLTHIOPHENE(1689-78-7)Related Product Information

• 3-AMINO-5-(TERT-BUTYL)THIOPHENE-2-CARBOXAMIDE
• POLY(3-BUTYLTHIOPHENE-2,5-DIYL),POLY(3-BUTYLTHIOPHENE-2,5-DIYL), REGIORA NDOM,POLY(3-BUTYLTHIOPHENE-2,5-DIYL), REGIO-R EGULAR
• 2-N-BUTYLTHIOPHENE, 98+%,2-n-Butylthiophene, 97+%,2-BUTYLTHIOPHENE,2-N-BUTYLTHIOPHENE
• 3-BUTYLTHIOPHENE,3-N-BUTYLTHIOPHENE,3-N-BUTYLTHIOPHENE 98+%
• 2,5-Dibromo-3-butylthiophene2,5-Dibromo-3-butylthiophene,2,5-DIBROMO-3-BUTYLTHIOPHENE
• 2-T-BUTYLTHIOPHENE
• N-(2-ACETYL-5-TERT-BUTYL-THIOPHEN-3-YL)-SUCCINAMIC ACID
• 3-AMINO-5-TERT-BUTYLTHIOPHENE-2-CARBOXYLIC ACID
• METHYL 3-AMINO-5-(TERT-BUTYL)THIOPHENE-2-CARBOXYLATE
• 2-ACETYL-3-AMINO-5-T-BUTYLTHIOPHENE,2-ACETYL-3-AMINO-5-TERT-BUTYLTHIOPHENE
• 3-(2-ACETYL-5-TERT-BUTYL-THIOPHEN-3-YLCARBAMOYL)-ACRYLIC ACID
• METHYL 5-(TERT-BUTYL)-3-[(2-CHLOROACETYL)AMINO]THIOPHENE-2-CARBOXYLATE
• 3,4-Di-tert-butylthiophene
• 5-TERT-BUTYLTHIOPHENE-2-BORONIC ACID
• ethyl 2-amino-4-tert-butylthiophene-3-carboxylate
• 2,5-Di-tert-butylthiophene
• 2-amino-4-tert-butylthiophene-3-carbonitrile
• METHYL 2-AMINO-4-TERT-BUTYLTHIOPHENE-3-CARBOXYLATE