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Eflornithine hydrochloride

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Eflornithine hydrochloride Basic information

Product Name:
Eflornithine hydrochloride
Synonyms:
  • RMI-71782
  • RMI-71782 HYDROCHLORIDE
  • 2-(difluoromethyl)-dl-ornithinehydrochloridehydrate
  • alpha-difluoromethylornithinehydrochloridehydrate
  • dl-ornithine,2-(difluoromethyl)-,monohydrochloride,hydrate
  • DFMO
  • DFMO HCL
  • DFMO HYDROCHLORIDE
CAS:
68278-23-9
MF:
C6H13ClF2N2O2
MW:
218.63
EINECS:
269-532-0
Product Categories:
  • Amino Acids and Derivatives
  • facial hair remover
Mol File:
68278-23-9.mol
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Eflornithine hydrochloride Chemical Properties

Melting point:
181-184°C
storage temp. 
Store at -20°C
solubility 
H2O: >10 mg/mL, soluble
form 
solid
color 
white
Water Solubility 
Soluble to 75 mM in water
CAS DataBase Reference
68278-23-9(CAS DataBase Reference)
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Safety Information

WGK Germany 
3

MSDS

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Eflornithine hydrochloride Usage And Synthesis

Uses

Antineoplastic; antiprotozoal.

Uses

DL-alpha-Difluoromethylornithine Hydrochloride is an irreversible inhibitor of ornithine decarboxylase.

Indications

Vaniqa (eflornithine hydrochloride 13.9%) cream is a unique topical cream that slows anagen hair growth by irreversibly blocking the enzyme ornithine decarboxylase. This enzyme produces polyamines in the hair matrix that are partially responsible for the growth of the anagen hair. The cream was tested only on the upper lip and chin region. The onset of action is usually within 8 weeks of starting the b.i.d. treatment, and the hair growth will return to baseline within 8 weeks of discontinuing the drug. Patients need to be reminded that this product does not remove hair but slows its growth in between whatever they use for hair removal.

brand name

Ornidyl (Sanofi Aventis); Vaniqa (Skinmedica).

storage

Desiccate at RT

Eflornithine hydrochlorideSupplier

3B Pharmachem (Wuhan) International Co.,Ltd.
Tel
821-50328103-801 18930552037
Email
3bsc@sina.com
Chembest Research Laboratories Limited
Tel
021-20908456
Email
sales@BioChemBest.com
Pure Chemistry Scientific Inc.
Tel
001-857-928-2050 or 1-888-588-9418
Email
sales@chemreagents.com
LGM Pharma
Tel
1-(800)-881-8210
Email
inquiries@lgmpharma.com
Shanghai Hanhong Scientific Co.,Ltd.
Tel
021-54306202 13764082696;
Email
info@hanhongsci.com
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Eflornithine hydrochloride(68278-23-9)Related Product Information