(D-PHE5,CYS6,11,N-ME-D-TRP8)-SOMATOSTATIN-14 (5-12) AMIDE
(D-PHE5,CYS6,11,N-ME-D-TRP8)-SOMATOSTATIN-14 (5-12) AMIDE Basic information
- Product Name:
- (D-PHE5,CYS6,11,N-ME-D-TRP8)-SOMATOSTATIN-14 (5-12) AMIDE
- Synonyms:
-
- H-D-Phe-Cys-Phe-N-Me-D-Trp-Lys-Thr-Cys-Thr-NH2 , (Disulfide bond)
- (D-Phe5,Cys6
- (N-Me-D-Trp4,Thr8)-Octreotide aMide, (N-Me-D-Trp4)-Octreotate aMide
- (D-Phe,Cys·11,N-Me-D-Trp)-Somatostatin-14 (5-12) amide
- (D-PHE5,CYS6,11,N-ME-D-TRP8)-SOMATOSTATIN-14 (5-12) AMIDE
- H-D-PHE-CYS-PHE-N-ME-D-TRP-LYS-THR-CYS-THR-NH2
- L-Threoninamide, D-phenylalanyl-L-cysteinyl-L-phenylalanyl-N-methyl-D-tryptophyl-L-lysyl-L-threonyl-L-cysteinyl-, cyclic (2→7)-disulfide
- (D-Phe?,Cys?·??,N-Me-D-Trp?)-Somatostatin-14 (5-12) amide
- CAS:
- 340821-13-8
- MF:
- C50H67N11O10S2
- MW:
- 1046.26
- Mol File:
- 340821-13-8.mol
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(D-PHE5,CYS6,11,N-ME-D-TRP8)-SOMATOSTATIN-14 (5-12) AMIDE Chemical Properties
- storage temp.
- -15°C
- Sequence
- {d-Phe}-Cys-Phe-{d-Trp(N-Me)}-Lys-Thr-Cys-Thr-NH2 (Disulfide bridge: Cys2-Cys7)
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(D-PHE5,CYS6,11,N-ME-D-TRP8)-SOMATOSTATIN-14 (5-12) AMIDE Usage And Synthesis
Uses
(D-Phe5,Cys6,11,N-Me-D-Trp8)-Somatostatin-14 (5-12) amide (Compound 4) is a somatostatin analog with Kds of 0.61, 11.05, 23.5, 1200 and >1000 nM for SSTR5, SSTR3, SSTR2, SSTR1 and SSTR4, respectively[1].
References
[1] Nikiforovich GV, et al. Molecular modeling suggests conformational scaffolds specifically targeting five subtypes of somatostatin receptors. Chem Biol Drug Des. 2007 Mar;69(3):163-9. DOI:10.1111/j.1747-0285.2007.00493.x
(D-PHE5,CYS6,11,N-ME-D-TRP8)-SOMATOSTATIN-14 (5-12) AMIDESupplier
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(D-PHE5,CYS6,11,N-ME-D-TRP8)-SOMATOSTATIN-14 (5-12) AMIDE(340821-13-8)Related Product Information
- (D-PHE5,CYS6,11,N-ME-D-TRP8)-SOMATOSTATIN-14 (5-12) AMIDE
- SOMATOSTATIN-28 (1-14)
- SOMATOSTATIN 28, CYCLIC
- CYCLO(7-AMINOHEPTANOYL-PHE-D-TRP-LYS-THR[BZL])
- H-PHE-TRP-LYS-THR-PHE-THR-SER-CYS-OH
- ALA-GLY-CYS-LYS-ASN-PHE-PHE-D-TRP-LYS-THR-PHE-THR-SER-CYS
- H-D-2-NAL-CYS-TYR-D-TRP-LYS-VAL-CYS-2-NAL-NH2
- TYR-GLY-CYS-LYS-ASN-PHE-PHE-TRP-LYS-THR-PHE-THR-SER-CYS
- (D-TRP8,D-CYS14)-SOMATOSTATIN-14
- BIOTINYL-SOMATOSTATIN-14