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METHYL 2-AMINO-5-BROMOBENZOATE

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METHYL 2-AMINO-5-BROMOBENZOATE Basic information

Product Name:
METHYL 2-AMINO-5-BROMOBENZOATE
Synonyms:
  • 2-Amino-5-bromobenzoic acid methyl ester~5-Bromoanthranilic acid methyl ester
  • 5-BROMOANTHRANILIC ACID METHYL ESTER 99+%
  • Methyl 2-amino-5-bromobenzoate,98%
  • 2-Amino-5-BromoBenzoic Acid methyl ester Methyl 2-amino-5-bromobenzoate
  • 4-Bromo-2-(methoxycarbonyl)aniline, Methyl 5-bromoanthranilate
  • 2-Amino-5-bromobenzoic Acid Methyl Ester Methyl 2-Amino-5-bromobenzoate 5-Bromoanthranilic Acid Methyl Ester
  • Methyl 2-aMino-5-broMobenzoate 96%
  • METHYL 5-BROMOANTHRANILATE
CAS:
52727-57-8
MF:
C8H8BrNO2
MW:
230.06
EINECS:
610-890-8
Product Categories:
  • amine | carboxylic ester| alkyl bromide
  • Anilines, Amides & Amines
  • Bromine Compounds
  • C8 to C9
  • Carbonyl Compounds
  • Esters
  • Aromatic Esters
  • Benzoic acid
  • Acids & Esters
Mol File:
52727-57-8.mol
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METHYL 2-AMINO-5-BROMOBENZOATE Chemical Properties

Melting point:
72-74 °C(lit.)
Boiling point:
286.3±20.0 °C(Predicted)
Density 
1.578±0.06 g/cm3(Predicted)
storage temp. 
Keep in dark place,Sealed in dry,Room Temperature
solubility 
DMSO, Methanol
pka
1.76±0.10(Predicted)
form 
Solid
color 
White
Water Solubility 
Soluble in water.
BRN 
972720
InChIKey
QVNYNHCNNGKULA-UHFFFAOYSA-N
CAS DataBase Reference
52727-57-8(CAS DataBase Reference)
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Safety Information

Hazard Codes 
Xi
Risk Statements 
36/37/38-37/38-36
Safety Statements 
26-36-37/39
WGK Germany 
3
HS Code 
29224999

MSDS

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METHYL 2-AMINO-5-BROMOBENZOATE Usage And Synthesis

Chemical Properties

White to light yellow crystal powder

Uses

Methyl 2-amino-5-bromobenzoate acts as a potential PqsD inhibitor against pseudomonas aeruginosa infections. It is also used in the preparation of hepatitis C virus NS5b RNA polymerase inhibitors. It is involved in plant growth-regulator activity.

Synthesis Reference(s)

Tetrahedron Letters, 35, p. 7055, 1994 DOI: 10.1016/0040-4039(94)88224-X

General Description

Molecules of methyl 2-amino-5-bromobenzoate are linked by N-H...O bonds and consists of zigzag chains running along the b-axis direction. The nonlinear optical single crystal of M2A5B grown by Sankaranarayanan-Ramasamy (SR) Unidirectional growth method shows good optical transparency and mechanical stability.

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