2-BROMO-5-PHENYLTHIOPHENE Chemical Properties

Melting point:

83 °C

Boiling point:

289℃

Density 

1.490

Flash point:

129℃

storage temp. 

under inert gas (nitrogen or Argon) at 2-8°C

form 

powder to crystal

color 

White to Light yellow

InChI

InChI=1S/C10H7BrS/c11-10-7-6-9(12-10)8-4-2-1-3-5-8/h1-7H

InChIKey

RVCTZBRMQZWVDA-UHFFFAOYSA-N

SMILES

C1(Br)SC(C2=CC=CC=C2)=CC=1

CAS DataBase Reference

29488-24-2

Safety Information

Hazard Codes 

T

Risk Statements 

20/21/22-36/37/38-41-25

Safety Statements 

22-26-36/37/39-45-39

RIDADR 

2811

HS Code 

2934999090

2-BROMO-5-PHENYLTHIOPHENE Usage And Synthesis

Synthesis

General procedure for the synthesis of 2-bromo-5-phenylthiophene from 2-phenylthiophene: 2-phenylthiophene (1.5 g, 9.4 mmol) was completely dissolved in chloroform (100 mL), followed by slow addition of N-bromosuccinimide (1.7 g, 9.4 mmol). The reaction mixture was stirred at room temperature for 30 min. Upon completion of the reaction, the solvent was completely removed by distillation under reduced pressure. Subsequently, ethanol was added to the residue at 0 °C and stirred for 20 min. The resulting precipitate was collected by filtration and the filtrate was dried under vacuum at room temperature to afford 2-bromo-5-phenylthiophene (2.2 g) in 100% yield.

References

[1] Patent: WO2008/153338, 2008, A2. Location in patent: Page/Page column 30-31
[2] Chemistry - An Asian Journal, 2014, vol. 9, # 9, p. 2542 - 2547,6
[3] Tetrahedron Letters, 2004, vol. 45, # 38, p. 7157 - 7161
[4] New Journal of Chemistry, 2009, vol. 33, # 6, p. 1362 - 1367
[5] Tetrahedron, 1997, vol. 53, # 30, p. 10357 - 10400

2-BROMO-5-PHENYLTHIOPHENE(29488-24-2)Related Product Information

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