(DHQD)2PHAL Chemical Properties

Melting point:

160 °C (dec.)(lit.)

alpha 

-262 º (C=1.2 IN MEOH)

Density 

1.3

storage temp. 

Inert atmosphere,Room Temperature

solubility 

Chloroform (Slightly), DMSO (Slightly), Methanol (Sparingly)

pka

9.61±0.70(Predicted)

form 

Solid

color 

White to Pale Yellow

optical activity

[α]22/D 262°, c = 1.2 in methanol

BRN 

5475678

InChIKey

YUCBLVFHJWOYDN-SOBQURILSA-N

CAS DataBase Reference

140853-10-7(CAS DataBase Reference)

Safety Information

Safety Statements 

22-24/25

WGK Germany 

3

F 

9

HS Code 

29392000

MSDS

• Language:English Provider:SigmaAldrich

(DHQD)2PHAL Usage And Synthesis

Uses

(DHQD)2PHAL is a monomeric cinchona alkaloid dimer used as a catalyst for asymmetric halogenations.

Uses

(DHQD)₂PHAL may be used as ligand for:

• Osmium trioxide catalyzed asymmetric dihydroxylation of olefins.
• Palladium catalyzed Suzuki-Miyaura coupling of aryl/heteroaryl halides with aryl boronic acids in aqueous medium and in the absence of phosphine/organic solvent.
• Copper(I)-catalyzed azide-alkyne cycloaddition reaction to synthesize 1,2,3-triazoles in water.

General Description

(DHQD)₂PHAL is a modified cinchona alkaloid derivative mainly used as a ligand for enantioselective catalysis.

(DHQD)2PHAL(140853-10-7)Related Product Information

• Hydrocortisone-17-butyrate
• (DHQD)2PYR
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• (DHQ)2PHAL
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• HYDROQUININE
• 3-METHOXYPYRIDAZINE
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• (DHQD)2PHAL
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• 4-(3-METHOXYPROPYL)PIPERIDINE
• 4-HEPTYLPYRIDINE