2,2-Dimethylbutyric acid Chemical Properties

Melting point:

-14°C

Boiling point:

94-96 °C/5 mmHg (lit.)

Density 

0.928 g/mL at 25 °C (lit.)

refractive index 

n20/D 1.4154(lit.)

Flash point:

175 °F

storage temp. 

Refrigerator

solubility 

Chloroform (Sparingly), Methanol (Slightly)

pka

pK1:5.03 (18°C)

form 

Liquid

color 

Clear colorless to pale yellow

Specific Gravity

0.928

Decomposition 

176-178 ºC

BRN 

1720666

InChIKey

VUAXHMVRKOTJKP-UHFFFAOYSA-N

LogP

1-2.3 at 20℃ and pH2.5-6.7

CAS DataBase Reference

595-37-9(CAS DataBase Reference)

NIST Chemistry Reference

Butanoic acid, 2,2-dimethyl-(595-37-9)

Safety Information

Hazard Codes 

Xi

Risk Statements 

36/37/38

Safety Statements 

26-36/37-36

RIDADR 

3265

WGK Germany 

3

HazardClass 

8

PackingGroup 

III

HS Code 

29156000

MSDS

• Language:English Provider:2,2-Dimethylbutyric acid
• Language:English Provider:SigmaAldrich
• Language:English Provider:ALFA

2,2-Dimethylbutyric acid Usage And Synthesis

Chemical Properties

Colorless to light yellow or light green liquid

Uses

2,2-Dimethylbutyrate (DMB) is a potential treatment for thalassemia and hemoglobinopathies.

Definition

ChEBI: A branched-chain fatty acid and metabolite of the lactone prodrug simvastatin, whose sodium salt is potentially useful for the treatment of thalassaemias and haemoglobinopathies.

Synthesis Reference(s)

Synthetic Communications, 19, p. 1945, 1989 DOI: 10.1080/00397918908052587

2,2-Dimethylbutyric acid(595-37-9)Related Product Information

• 2,2-DIMETHYLVALERIC ACID
• N,N-Dimethylpropionamide
• 2,2-Dimethylbutyryl chloride
• CELLULOSE ACETATE BUTYRATE
• Citric acid
• Chlorambucil
• Folic acid
• Butyric Acid
• MCPB
• Indole-3-butyric acid
• Ethyl 2-(Chlorosulfonyl)acetate
• 4-Aminobutyric acid
• Hydrocortisone-17-butyrate
• 2-Methyl butyric acid
• Ascoric Acid
• 3,3-Dimethylbutyric acid
• 2-Oxo-3,3-dimethylbutyric acid
• L-tert-Leucine