2,6-DIFLUORO-3-NITROBENZOIC ACID Chemical Properties

Melting point:

92-96°C

Boiling point:

335.5±42.0 °C(Predicted)

Density 

1.661

storage temp. 

Sealed in dry,Room Temperature

pka

1.48±0.29(Predicted)

form 

powder to crystal

color 

White to Light yellow

CAS DataBase Reference

83141-10-0(CAS DataBase Reference)

Safety Information

Hazard Codes 

Xi

Risk Statements 

36/37/38

Safety Statements 

26-36/37/39-24/25

Hazard Note 

Irritant/Keep Cold

HazardClass 

IRRITANT

HS Code 

29163990

2,6-DIFLUORO-3-NITROBENZOIC ACID Usage And Synthesis

Chemical Properties

Light yellow solid

Uses

2,6-Difluoro-3-nitrobenzoic acid is a benzoic acid derivative that contains reactive substituent fluorine atoms and nitro groups in its molecular structure. The substance is mainly used as a reagent for organic synthesis or as a component of pharmaceutical intermediates. It is used in the synthesis of B-Raf kinase inhibitors, such as vemurafenib, which causes programmed cell death (apoptosis) in melanoma cell lines. In addition, it is used in the synthesis of fluoroquinolone antibacterial agents.

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