Basic information Safety Supplier Related

7-Fluoro-4-quinazolone

Basic information Safety Supplier Related

7-Fluoro-4-quinazolone Basic information

Product Name:
7-Fluoro-4-quinazolone
Synonyms:
  • BUTTPARK 76\07-32
  • 7-FLUOROQUINAZOLIN-4-OL
  • 7-Fluoro-4-quinazolone
  • 7-Fluoroquinazolin-4(3H)one
  • 7-Fluoroquinazolin-4-one
  • 7-Fluoroquinazolin-4(1H)-one, 7-Fluoroquinazolin-4-ol, 3,4-Dihydro-7-fluoro-4-oxoquinazoline
  • EOS-61781
  • 7-Fluoro-1h-quinazolin-4-one
CAS:
16499-57-3
MF:
C8H5FN2O
MW:
164.14
Product Categories:
  • API intermediates
  • Fused Ring Systems
Mol File:
16499-57-3.mol
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7-Fluoro-4-quinazolone Chemical Properties

Melting point:
246.0 to 250.0 °C
Boiling point:
293.3±42.0 °C(Predicted)
Density 
1.44±0.1 g/cm3(Predicted)
storage temp. 
Sealed in dry,Room Temperature
form 
powder to crystal
pka
0.51±0.20(Predicted)
color 
White to Gray to Red
InChIKey
KCORZHJVTZIZFD-UHFFFAOYSA-N
CAS DataBase Reference
16499-57-3(CAS DataBase Reference)
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Safety Information

Hazard Codes 
Xi
HazardClass 
IRRITANT
HS Code 
2933599590
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7-Fluoro-4-quinazolone Usage And Synthesis

Uses

7-Fluoro-4(3H)-quinazolinone is a fluorinated quinazolin-4(3H)-one with poly(ADP-ribose)polymerase-1 (PARP-1) inhibitory activity. 7-Fluoro-4(3H)-quinazolinone is also used as an intermediate in the preparation of the aurora kinase inhibitor AZD1152 (A808100).

Uses

7-Fluoro-4-quinazolone is a fluorinated quinazolin-4(3H)-one with poly(ADP-ribose)polymerase-1 (PARP-1) inhibitory activity.It is also used as an intermediate in the preparation of the aurora kinase inhibitor AZD1152 (A808100).

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