ISOXYL Chemical Properties

Melting point:

134-145°

Boiling point:

508.5±60.0 °C(Predicted)

Density 

1.0659 (rough estimate)

refractive index 

1.6360 (estimate)

storage temp. 

Store at -20°C

solubility 

DMF: 30 mg/ml; DMSO: 30 mg/ml; Ethanol: 1 mg/ml

form 

A crystalline solid

pka

12.44±0.70(Predicted)

ISOXYL Usage And Synthesis

Originator

Tiocarlide,Ciba,W. Germany,1963

Definition

ChEBI: Tiocarlide is a member of thioureas.

Manufacturing Process

100 parts by weight of p-isoamyloxyaniline are refluxed for 6 hours with 34 parts by volume of carbon disulfide, 300 parts by volume of ethanol and 5 parts by weight of potassium ethyl xanthate. The reaction mixture is then cooled and the formed 1,3-bis-(p-isoamyloxyphenyl)-2-thiourea is filtered off, washed with a small amount of ethanol and water, and recrystallized from ethanol. The thus-obtained product melts at 134°C to 145°C.

Therapeutic Function

Antitubercular

ISOXYL(910-86-1)Related Product Information

• ISOXYL
• 1-(4-ETHOXYPHENYL)-2-THIOUREA
• ISOXYL
• Etocarlide