DIDS Chemical Properties

Melting point:

>300°C

Density 

1.54

storage temp. 

2-8°C

solubility 

0.1 M potassium bicarbonate: 50 mg/mL

form 

powder

color 

yellow

Stability:

Recommend Desiccate and Storage at -20°C

CAS DataBase Reference

67483-13-0

Safety Information

Hazard Codes 

Xn

Risk Statements 

36/37/38-42-26-22

Safety Statements 

22-26-36/37/38

WGK Germany 

3

F 

3-10-21

HS Code 

29309090

MSDS

• Language:English Provider:SigmaAldrich
• Language:English Provider:ACROS

DIDS Usage And Synthesis

Chemical Properties

yellow to yellow-green or brown powder

Uses

Stilbene disulfonates have been employed to inhibit anion transport in a large number of mammalian cell types (GABA, Cl-). Some stilbene disulfonates can bind specifically to proteins that are not anion transporters. DIDS reacts with CD4 glycoprotein on T helper lymphocytes and macrophages, blocking HIV type-1 growth at multiple stages of the viral life cycle. Fluorescence: max. Abs. l = 341, max. Em. l = 415 (in water)

Uses

ATP transport inhibitor, anion transport inhibitor, antiulcer

Uses

complexing agent for potassium ions

Uses

DIDS is a stilbene sulfonate that inhibits anionic transport. It has been used to inhibit Cl- uptake through plasma membrane-localized Cl- channels in order to study chloride transport. It also effectively inhibits various sodium-coupled bicarbonate transporters.

storage

Store at +4°C

DIDS(67483-13-0)Related Product Information

• 3-Chlorostyrene
• Oxyresveratrol
• 4,4'-DIISOTHIOCYANATODIHYDROSTILBENE-2,2'- DISULFONIC ACID, DISODIUM SALT (H2DIDS)
• 3H2-DIDS
• H2-DIDS, DISODIUM SALT
• DIDS, Disodium 4,4μ-diisothiocyanatostilbene-2,2μ-disulfonate
• dihydro-DIDS
• H2-DIDS
• 4,4'-DIISOTHIOCYANATOSTILBENE-2,2'-DISULFONIC ACID, DISODIUM SALT (DIDS)