Ethyl carbazate
Ethyl carbazate Basic information
- Product Name:
- Ethyl carbazate
- Synonyms:
-
- (Ethoxycarbonyl)hydrazide
- (Monocarbethoxy)hydrazine
- 1-(Carbethoxy)hydrazine
- 1-(Ethoxycarbonyl)hydrazine
- AKOS 90785
- Ethoxycarbonylhydrazine~Ethyl hydrazinocarboxylate
- ETHOXY CARBONYLHYDRAZINE
- ETHOXY FORMHYDRAZINE
- CAS:
- 4114-31-2
- MF:
- C3H8N2O2
- MW:
- 104.11
- EINECS:
- 223-903-3
- Product Categories:
-
- Pharmaceutical Intermediates
- Miscellaneous
- Building Blocks
- Chemical Synthesis
- Nitrogen Compounds
- Organic Building Blocks
- Protected Amines
- bc0001
- Mol File:
- 4114-31-2.mol
Ethyl carbazate Chemical Properties
- Melting point:
- 44-47 °C (lit.)
- Boiling point:
- 108-110 °C/22 mmHg (lit.)
- Density
- 1.2719 (rough estimate)
- refractive index
- 1.4715 (estimate)
- Flash point:
- 187 °F
- storage temp.
- Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
- pka
- 10.72±0.20(Predicted)
- form
- Powder
- color
- White to cream
- Water Solubility
- Very soluble in water.
- Sensitive
- Moisture Sensitive
- BRN
- 878265
- InChIKey
- VYSYZMNJHYOXGN-UHFFFAOYSA-N
- CAS DataBase Reference
- 4114-31-2(CAS DataBase Reference)
- NIST Chemistry Reference
- Hydrazinecarboxylic acid, ethyl ester(4114-31-2)
- EPA Substance Registry System
- Hydrazinecarboxylic acid, ethyl ester (4114-31-2)
Safety Information
- Hazard Codes
- Xi,T
- Risk Statements
- 36/37/38-25
- Safety Statements
- 26-36-45
- RIDADR
- 2811
- WGK Germany
- 3
- RTECS
- FE2545000
- TSCA
- Yes
- HazardClass
- 6.1
- PackingGroup
- III
- HS Code
- 29280090
MSDS
- Language:English Provider:Carboethoxy hydrazine
- Language:English Provider:SigmaAldrich
- Language:English Provider:ACROS
- Language:English Provider:ALFA
Ethyl carbazate Usage And Synthesis
Chemical Properties
Off-white crystals.
Uses
Synthetic intermediate.
Uses
Prepare 4-phenylurazole from ethyl carbazate and then oxidize the urazole with gaseous dinitrogen tetroxide to yield 4-phenyl-1,2,4-tri- azoline-3,5-dione la. Modification of the ethyl carbazate procedure in which analytically pure monoalkylhydrazine hydrochlorides were isolated in greater than 90% yield, starting from a ketone or aldehyde. Treatment of primary amines is with chloroamine or hydroxylamine-0-sulfonic acid and the condensation of a carbonyl compound with ethyl carbazate. The FeCl 3 -catalyzed reaction of ethyl carbazate (2 b) proceeded readily to give β-hydroxyester 3 b in better yield. A new one-pot neat synthesis of some 5-aryl-2,4-dihydro-3H-1,2,4-triazol-3-ones through cyclocondensation of ethyl carbazate with aryl nitriles catalyzed by DMAP as an efficient and basic nucleophilic catalyst is described.
Hazard
Irritant.
Purification Methods
Fractionate the carbazate using a Vigreux column (p 11) until the distillate crystallises [Allen & Bell Org Synth Coll Vol III 404 1955, Beilstein 3 IV 174].
Ethyl carbazate Preparation Products And Raw materials
Raw materials
Preparation Products
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