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Cefuroxime 1-acetoxyethyl ester

Basic information Safety Supplier Related

Cefuroxime 1-acetoxyethyl ester Basic information

Product Name:
Cefuroxime 1-acetoxyethyl ester
Synonyms:
  • 1-(acetyloxy)ethylest
  • cxm-ax
  • (6R-(6alpha,7beta(Z)))-3-(((Aminocarbonyl)oxy)methyl)-7-((2-furanyl(methoxyimino)a cetyl)-amino)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid 1-(acetyloxy)ethyl ester
  • Cefuroxime 1-acetoxyethyl ester
  • [6R-[6α,7β(Z)]]-3-[(Aminocarbonyloxy)methyl]-7-[2-(furan-2-y1)-2-(methoxyimino)acetamido]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-car-boxylic acid(2-acetoxy)ethylester
  • Elobact:Oraxim
  • Maxitil
  • (6R)-3-[[(Aminocarbonyl)oxy]methyl]-7α-[[2-furanyl[(Z)-methoxyimino]acetyl]amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid 1-acetoxyethyl ester
CAS:
64544-07-6
MF:
C20H22N4O10S
MW:
510.47
EINECS:
638-760-6
Product Categories:
  • Pharmaceutical intermediates
  • Pharmaceutical intermediate
  • Chiral Reagents
  • Heterocycles
  • Intermediates & Fine Chemicals
  • VIROPTIC
  • Pharmaceuticals
  • Sulfur & Selenium Compounds
  • 64544-07-6
Mol File:
64544-07-6.mol
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Cefuroxime 1-acetoxyethyl ester Chemical Properties

Melting point:
175-180 °C
Boiling point:
250°C (rough estimate)
Density 
1.3927 (rough estimate)
refractive index 
1.6000 (estimate)
storage temp. 
-20°C
solubility 
DMSO: soluble1mg/mL
form 
powder
pka
8.31±0.60(Predicted)
color 
white to off-white
InChIKey
KEJCWVGMRLCZQQ-UXXYIVIXSA-N
CAS DataBase Reference
64544-07-6(CAS DataBase Reference)
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Safety Information

WGK Germany 
2
HS Code 
2941906000
Hazardous Substances Data
64544-07-6(Hazardous Substances Data)
Toxicity
LD50 oral in rabbit: 200mg/kg
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Cefuroxime 1-acetoxyethyl ester Usage And Synthesis

Chemical Properties

White to Off-White Solid

Uses

It is the 1-(acetyloxy) ethyl ester of Cefuroxime (C248060), an injectable second generation cephalosporin with an excellent antibacterial activity. This ester has a broader spectrum of activity than cephalexin (first-generation) and is widely used to treat respiratory tract infections. Antibacterial.

Uses

antiviral (opthalmic)

Uses

Cefuroxime 1-acetoxyethyl ester is an injectable second generation cephalosporin with an excellent antibacterial activity. This ester has a broader spectrum of activity than cephalexin (first-generation) and is widely used to treat respiratory tract infections.

Definition

ChEBI: Cefuroxime axetil is a cephalosporin.

Cefuroxime 1-acetoxyethyl ester Preparation Products And Raw materials

Raw materials

Cefuroxime 1-acetoxyethyl ester Supplier

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