2-NITROFURAN
2-NITROFURAN Basic information
- Product Name:
- 2-NITROFURAN
- Synonyms:
-
- 2-NITROFURAN
- 2-nitro-fura
- 2-Nitrofurane
- 5-Nitrofuran
- Furan, 2-nitro-
- Nitrofuran
- NSC 59983
- CAS:
- 609-39-2
- MF:
- C4H3NO3
- MW:
- 113.07
- Product Categories:
-
- Building Blocks
- Furans
- Heterocyclic Building Blocks
- Heterocycles
- Intermediates & Fine Chemicals
- Pharmaceuticals
- Mol File:
- 609-39-2.mol
2-NITROFURAN Chemical Properties
- Melting point:
- 29-33 °C (lit.)
- Boiling point:
- 84 °C/13 mmHg (lit.)
- Density
- 1.5808 (rough estimate)
- refractive index
- 1.4543 (estimate)
- Flash point:
- 191 °F
- storage temp.
- 2-8°C
- solubility
- Chloroform, Methanol
- form
- Solid
- color
- Clear Colorless to Off-White
- Stability:
- Stable. Incompatible with strong oxidizing agents.
- CAS DataBase Reference
- 609-39-2
Safety Information
- Hazard Codes
- Xn
- Risk Statements
- 20/21/22-40
- Safety Statements
- 7-23-36/37/39-45
- RIDADR
- UN 1325 4.1/PG 2
- WGK Germany
- 3
- RTECS
- LU3100000
MSDS
- Language:English Provider:SigmaAldrich
2-NITROFURAN Usage And Synthesis
Chemical Properties
solid
Uses
Nitrofurans are a class of broad-spectrum antibacterial compounds that are commonly added to water to destroy bacteria. However, nitrofurans have recently been withdrawn for use in the United States by the US Food and Drug Administration (FDA). Now, 2-nitrofuran is used as a minor antimicrobial in veterinary medicine.
Uses
2-NITROFURAN is a minor antimicrobial used in veterinary medicine.
Definition
ChEBI: 2-nitrofuran is a member of furans and a C-nitro compound.
Environmental Fate
2-Nitrofuran is a yellow crystalline solid with molecular weight
of 113.07152 g mol-1. The boiling point of 2-nitrofuran is
84 ℃ at 17 hPa and the melting point is 29–33 ℃. It is
a flammable solid. Its flash point is 88 ℃ (closed cup). Vapor
pressure is 0.398mmHg at 25 ℃. This compound is soluble in
H2O and ethanol. Its density is 1.344 g cm-3.
The partition behavior of 2-nitrofuran in water, sediment,
and soil is 0.8. No data are available on its environmental
persistency (degradation/speciation), long-range transport,
bioaccumulation, and biomagnification. This chemical is
stable but it is incompatible with strong oxidizing agents.
Toxicity evaluation
2-Nitrofuran reacts with DNA to form complexes, induces interstrand cross-links, produces alkali-labile lesions, and interferes with nucleic acid synthesis. Removal of the nitro group decreases the mutagenic activity.
2-NITROFURAN Preparation Products And Raw materials
Raw materials
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