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Bis(3-nitrophenyl) disulfide

Basic information Safety Supplier Related

Bis(3-nitrophenyl) disulfide Basic information

Product Name:
Bis(3-nitrophenyl) disulfide
Synonyms:
  • 1-NITRO-3-[(3-NITROPHENYL)DITHIO]BENZENE
  • METAMETADINITRODIPHENYLDISULPHIDE
  • Bis(3-nitrophenyl) disulfide, Nitrophenide
  • Hinagen
  • Megasul
  • Bis(3-nitrophenyl) persulfide
  • Bis(m-nitrophenyl) persulfide
  • Bis(m-nitrophenyl)persulfide
CAS:
537-91-7
MF:
C12H8N2O4S2
MW:
308.33
EINECS:
208-677-6
Product Categories:
  • Phenyls & Phenyl-Het
  • Phenyls & Phenyl-Het
Mol File:
537-91-7.mol
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Bis(3-nitrophenyl) disulfide Chemical Properties

Melting point:
78-80 °C(lit.)
Boiling point:
443.6±30.0 °C(Predicted)
Density 
1.5285 (rough estimate)
refractive index 
1.6510 (estimate)
solubility 
soluble in Tetrahydrofuran
form 
powder to crystal
color 
Light yellow to Brown to Dark green
Sensitive 
Stench
Merck 
14,6618
InChI
InChI=1S/C12H8N2O4S2/c15-13(16)9-3-1-5-11(7-9)19-20-12-6-2-4-10(8-12)14(17)18/h1-8H
InChIKey
ODOFDWDUSSFUMN-UHFFFAOYSA-N
SMILES
S(C1=CC=CC([N+]([O-])=O)=C1)SC1=CC=CC([N+]([O-])=O)=C1
CAS DataBase Reference
537-91-7(CAS DataBase Reference)
EPA Substance Registry System
Disulfide, bis(3-nitrophenyl) (537-91-7)
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Safety Information

Hazard Codes 
N
Risk Statements 
50/53
Safety Statements 
60-61-24/25
RIDADR 
UN 3077 9/PG 3
WGK Germany 
3
RTECS 
JO1550000
Hazard Note 
Harmful/Stench
HS Code 
29309090

MSDS

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Bis(3-nitrophenyl) disulfide Usage And Synthesis

Uses

3-Nitrophenyl disulfide (Bis(3-Nitrophenyl) disulfide) is an inhibitor of mannitol-1-phosphate dehydrogenase (M1PDH) with IC50 of 3 μM. 3-Nitrophenyl disulfide has antiparasitic activity[1].

References

[1] Allocco JJ, et al. Nitrophenide (Megasul) blocks Eimeria tenella development by inhibiting the mannitol cycle enzyme mannitol-1-phosphate dehydrogenase. J Parasitol. 2001 Dec;87(6):1441-8. DOI:10.1645/0022-3395(2001)087[1441:NMBETD]2.0.CO;2

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