Sulfacetamide sodium Chemical Properties

Melting point:

257 °C

storage temp. 

Keep in dark place,Inert atmosphere,Room temperature

Water Solubility 

Soluble in water

solubility 

DMF: 20 mg/mL; DMSO: 15 mg/mL; Ethanol: 1 mg/mL; PBS (pH 7.2): 5 mg/mL

form 

Solid

color 

White to Almost white

Merck 

14,8899

InChI

InChI=1S/C8H10N2O3S.Na/c1-6(11)10-14(12,13)8-4-2-7(9)3-5-8;/h2-5H,9H2,1H3,(H,10,11);/q;+1/p-1

InChIKey

PQMSFAORUFMASU-UHFFFAOYSA-M

SMILES

S(=O)(=O)(C1C=CC(N)=CC=1)N([Na])C(=O)C

CAS DataBase Reference

127-56-0

EPA Substance Registry System

Acetamide, N-[(4-aminophenyl)sulfonyl]-, monosodium salt (127-56-0)

Safety Information

Hazard Codes 

Xi

Risk Statements 

36/37/38

Safety Statements 

26-36

RIDADR 

3249

WGK Germany 

3

RTECS 

AC8480000

HS Code 

2935.90.9500

HazardClass 

6.1(b)

PackingGroup 

III

MSDS

• Language:English Provider:SigmaAldrich
• Language:English Provider:ALFA

Sulfacetamide sodium Usage And Synthesis

Description

Sulfacetamide is a sulfonamide antibiotic that is bacteriostatic against Gram-positive and Gram-negative bacteria. It inhibits dihydropteroate synthase (IC₅₀ = 9.6 μM), blocking the synthesis of dihydrofolic acid, and also inhibits bacterial 4-aminobenzoic acid , which is required for the synthesis of folic acid.

Chemical Properties

White crystalline powder, melting point 183°C. Freely soluble in water, slightly soluble in ethanol, slightly soluble in acetone. No stink bugs, slightly bitter taste.

Uses

Sulfacetamide Sodium Salt is an antibiotic that blocks synthesis of dihydrofolic acid by inhibiting the enzyme dihydropteroate synthase. It can be used in biological study to explore topical application of benzoyl peroxide, antibiotics, sulfur and sodium sulfacetamide, azelaic acid for treatment of acne vulgaris in humans.

Uses

Sulfacetamide Sodium is an anti-biotic

Definition

ChEBI: An organic sodium salt that is the monosodium salt of sulfacetamide.

brand name

Bleph (Allergan); Cetamide (Alcon); Klaron (Sanofi Aventis); Ocusulf (MIZA); Sodium Sulamyd (Schering); Sulf (Novartis); Sulfacel (Optopics); Sulfair (Pharmafair); Sulten (Bausch & Lomb).

References

[1] VIKRAM PRABHU  John K  Helen Lui. Arabidopsis dihydropteroate synthase: General properties and inhibition by reaction product and sulfonamides[J]. Phytochemistry, 1997, 45 1: Pages 23-27. DOI: 10.1016/s0031-9422(96)00793-5

Sulfacetamide sodium (127-56-0)Related Product Information

• Sodium chlorite
• Sodium amide
• Sodium benzoate
• Acesulfame
• Acetaminophen
• Acetamide
• Sulfamic acid monosodium salt
• Sodium bicarbonate
• Sodium chloride
• Sulfadimethoxine sodium salt
• Sulfacetamide
• SULFOACETIC ACID DISODIUM SALT
• Sodium citrate
• Sodium sulfate
• 3,4'-DIAMINODIPHENYLMETHANE
• 4-Amino-benzenesulfonic acid monosodium salt
• Sodium N-cyclohexylsulfamate
• Molasses