3-Nitropyridine Chemical Properties

Melting point:

35-40 °C

Boiling point:

216°C

Density 

1,33 g/cm³

refractive index 

1.4800 (estimate)

Flash point:

216°C

storage temp. 

Flammables area

solubility 

soluble in Methanol

form 

Liquid

pka

pK1:0.79(+1) (25°C,μ=0.02)

color 

Clear colorless

BRN 

111969

CAS DataBase Reference

2530-26-9(CAS DataBase Reference)

Safety Information

Hazard Codes 

Xn-F,Xn,F

Risk Statements 

20/21/22-11-41-37/38-22

Safety Statements 

37/39-26-16-39

RIDADR 

2811

WGK Germany 

3

HazardClass 

6.1

PackingGroup 

III

HS Code 

29333999

MSDS

• Language:English Provider:ACROS
• Language:English Provider:ALFA

3-Nitropyridine Usage And Synthesis

Chemical Properties

white to yellow needle-like crystals

Uses

3-Nitropyridine is used in the novel synthesis of biologically active nitro heterocyclic compounds.

Synthesis

In 1993 Suzuki and co-workers reported the nitration of pyridine with nitrogen dioxide and ozone in dichloromethane at room temperature. They obtained a 3.5 % yield of 3-nitropyridine and 1.2 % of 3,5-dinitropyridine.

3-Nitropyridines can also be synthesized by oxidation of 3-aminopyridine with hydrogen peroxide in fuming sulphuric acid in 45% yield. Nitration of 2,6-dichloropyridine with nitronium tetrafluoroborate gave a 11% yield of 3-nitropyridine after dehalogenation. 3-nitropyridine has also been prepared from 2- chloro-3-nitropyridine.

3-Nitropyridine(2530-26-9)Related Product Information

• Nicotinic acid
• Ethyl 2-aminopyridine-3-carboxylate
• NICOTINIC-D4 ACID
• Isonicotinic acid
• 2-Aminopyridine N-oxide
• 3,5-DINITROPYRIDINE
• 2-BROMOPYRIDINE N-OXIDE
• 2-Hydroxy-5-pyridinecarboxylic acid
• 2,5-PYRIDINEDICARBOXYLIC ACID
• 3-Ethylpyridine
• 5-Ethyl-2-methylpyridine
• 2,2'-Bipyridine-5,5'-dicarboxylic acid
• 5-Chloro-6-hydroxy-3-pyridinecarboxylic acid
• 5-NITRONICOTINIC ACID
• Methyl nicotinate
• 6-Methylpyridine-3-carboxylic acid
• MEA-BENZOATE
• 2-Amino-3-nitropyridine