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BERBERINE CHLORIDE

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BERBERINE CHLORIDE Basic information

Product Name:
BERBERINE CHLORIDE
Synonyms:
  • Berberine (berberine hydrochloride)
  • Berberine chloride hydrate 97%
  • 9,10-DiMethoxy-5,6-dihydro-[1,3]dioxolo[4,5-g]isoquinolino[3,2-a]isoquinolin-7-iuM chloride hydrate
  • Berberine chloride hydrate technical, >=90% (AT)
  • Benzo[g]-1,3-benzodioxolo[5,6-a]quinolizinium,5,6-dihydro-9,10-dimethoxy-, chloride, hydrate (1:1:)
  • LABOTEST-BB LT00440956
  • CI 75160
  • BERBERIN HCL
CAS:
141433-60-5
MF:
C20H20ClNO5
MW:
389.83
EINECS:
211-195-9
Product Categories:
  • Alkaloids
  • Biochemistry
  • Miscellaneous Natural Products
  • Isoquinoline Alkaloids
Mol File:
141433-60-5.mol
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BERBERINE CHLORIDE Chemical Properties

Melting point:
204-206 °C (dec.)
storage temp. 
Sealed in dry,Room Temperature
solubility 
DMSO (Slightly), Methanol (Slightly)
form 
Solid
Colour Index 
75160
color 
Pale Yellow to Yellow
Water Solubility 
Soluble in water.
Sensitive 
Light Sensitive
Merck 
14,1154
BRN 
3836585
Stability:
Hygroscopic
InChIKey
VKJGBAJNNALVAV-UHFFFAOYSA-M
CAS DataBase Reference
141433-60-5(CAS DataBase Reference)
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Safety Information

Hazard Codes 
Xn
Risk Statements 
20/21/22
WGK Germany 
2
RTECS 
DR9866400
3-10
TSCA 
Yes
HS Code 
29399990

MSDS

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BERBERINE CHLORIDE Usage And Synthesis

Description

This alkaloid occurs together with Neprotine (q.v.) in Berberis insignis Hook, B. umbellata Wall and Mahonia nepalensis DC. (Syn. Berberis nepalensis Spreng.). It is optically inactive and crystallizes from H2O with 5.5 H2O. It yields crystal_x0002_line salts, e.g. the nitrate, m.p. 265-7°C (dec.); sulphate, m.p. 271-3°C (dec.) and the picrate, m.p. 231°C (dec.). The base also furnishes a methyl ether, m.p. 265°C and on catalytic hydrogenation gives the tetrahydro derivative, m.p. 213-5°C (dec.). The ultraviolet spectrum resembles that of berberine (q.v.). Oxidation with KMn04 in Me2CO gives hemipinic acid, identified as the ethylimide, m.p. 90°C.

Uses

Primarily for the treatment of gastroenteritis, dysentery and other intestinal infections and conjunctivitis, purulent otitis media.

References

Orekhov.,J. Amer. Pharm. Assoc., 30,247, (1941)
Chatterjee., ibid, 33,205,210 (1944)

BERBERINE CHLORIDE Preparation Products And Raw materials

Preparation Products

BERBERINE CHLORIDESupplier

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