BERBERINE CHLORIDE Chemical Properties

Melting point:

204-206 °C (dec.)

storage temp. 

Sealed in dry,Room Temperature

solubility 

DMSO (Slightly), Methanol (Slightly)

form 

Solid

Colour Index 

75160

color 

Pale Yellow to Yellow

Water Solubility 

Soluble in water.

Sensitive 

Light Sensitive

Merck 

14,1154

BRN 

3836585

Stability:

Hygroscopic

InChIKey

VKJGBAJNNALVAV-UHFFFAOYSA-M

CAS DataBase Reference

141433-60-5(CAS DataBase Reference)

Safety Information

Hazard Codes 

Xn

Risk Statements 

20/21/22

WGK Germany 

2

RTECS 

DR9866400

F 

3-10

TSCA 

Yes

HS Code 

29399990

MSDS

• Language:English Provider:SigmaAldrich

BERBERINE CHLORIDE Usage And Synthesis

Description

This alkaloid occurs together with Neprotine (q.v.) in Berberis insignis Hook, B. umbellata Wall and Mahonia nepalensis DC. (Syn. Berberis nepalensis Spreng.). It is optically inactive and crystallizes from H2O with 5.5 H2O. It yields crystal_x0002_line salts, e.g. the nitrate, m.p. 265-7°C (dec.); sulphate, m.p. 271-3°C (dec.) and the picrate, m.p. 231°C (dec.). The base also furnishes a methyl ether, m.p. 265°C and on catalytic hydrogenation gives the tetrahydro derivative, m.p. 213-5°C (dec.). The ultraviolet spectrum resembles that of berberine (q.v.). Oxidation with KMn04 in Me2CO gives hemipinic acid, identified as the ethylimide, m.p. 90°C.

Uses

Primarily for the treatment of gastroenteritis, dysentery and other intestinal infections and conjunctivitis, purulent otitis media.

References

Orekhov.,J. Amer. Pharm. Assoc., 30,247, (1941)
Chatterjee., ibid, 33,205,210 (1944)

BERBERINE CHLORIDE(141433-60-5)Related Product Information

• Sodium chloride
• Ammonium chloride
• Chloral hydrate
• BERBERINE CHLORIDE,Berberine chloride form,Berberinehydrochloride，Berberine chloride form,Berberine chloride ,98%,BERBERINE CHLORIDE(AHP)
• Berberine
• BERBERINE CHLORIDE 2-HYDRATE,BERBERINE CHLORIDE DIHYDRATE
• Methylene Chloride
• hydrate
• hydrazine hydrate
• BERBERINE CHLORIDE
• BERBERINE CHLORIDE(RG)
• BERBERINE CHLORIDE EXTRACT JP 12
• BERBERINE, ACETONE ADDUCT
• 2-​[[(2-​ethylphenyl)​(2-​hydroxyethyl)​amino]​methyl]​-​3,​3-​difluoro-Propanenitrile
• Berberine Hcl