1,1'-DIOCTADECYL-3,3,3',3'-TETRAMETHYLINDOCARBOCYANINE PERCHLORATE Chemical Properties

Melting point:

68 °C (dec.)(lit.)

storage temp. 

2-8°C

solubility 

DMF: soluble

form 

crystals or powder

color 

Burgundy to purples-violet

λmax

549 nm

BRN 

8251870

Biological Applications

Detecting cell fusion,cell adhesion,cell migration,cell proliferation; membrane fusion assay; exocytosis and/or endocytosis assay

InChIKey

JVXZRNYCRFIEGV-UHFFFAOYSA-M

CAS DataBase Reference

41085-99-8

Safety Information

Safety Statements 

22-24/25

WGK Germany 

3

F 

8

HS Code 

29339900

MSDS

• Language:English Provider:SigmaAldrich

1,1'-DIOCTADECYL-3,3,3',3'-TETRAMETHYLINDOCARBOCYANINE PERCHLORATE Usage And Synthesis

Uses

1,1'-Dioctadecyl-3,3,3',3'-tetramethylindocarbocyanine per chlorate is a lipophilic dye used to record membrane voltage for fluidity studies. This retrograde stain is useful in staining neurons?in vitro?and?in vivo?because the stain is relatively nontoxic to cell bodies and the dye is retained in neurons. In addition, 1,1'-Dioctadecyl-3,3,3',3'-tetramethylindocarbocyanine per chlorate is an ideal retrograde and anterograde tracer to label the processes as well as the cell bodies of cultured neurons.

Uses

1,1′-Dioctadecyl-3,3,3′,3′-tetramethylindocarbocyanine perchlorate has been used in fluorescent labelling of mesenchymal stem cells (MSCs)?and cerebral cortex. It has also been used in electromyogram (EMG) to determine awake and anesthetized states in mice.

Uses

1,1'-Di-n-octadecyl-3,3,3',3'-tetramethylindocarbocyanine perchlorate is used primarily for optical recordings of membrane voltage and for studies of membrane fluidity. Retrograde stain for neurons; provides intense, long-lasting staining of live neurons in vivo and in vitro.

General Description

DiI is a Dye Aye, a chemical with CAS number 41085-99-8. It is a fluorescent lipophilic cationic indocarbocyanine dye, which is usually made as a perchlorate salt. Mostly used for scientific staining purposes, such as single molecule imaging, fate mapping and neuronal tracing (as DiI is retained in the lipid bilayers).

Biochem/physiol Actions

Lipophilic carbocyanine dye used primarily for optical recordings of membrane voltage and for studies of membrane fluidity. Retrograde stain for neurons; provides intense, long-lasting staining of live neurons in vivo and in vitro.

1,1'-DIOCTADECYL-3,3,3',3'-TETRAMETHYLINDOCARBOCYANINE PERCHLORATE(41085-99-8)Related Product Information

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