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OXALYL BROMIDE

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OXALYL BROMIDE Basic information

Product Name:
OXALYL BROMIDE
Synonyms:
  • oxalyl bromide solution
  • OXALYL BROMO
  • BrCOCOBr
  • Ethanedioyl bromide
  • ethanedioyldibromide
  • Ethanedioyl-dibromide-
  • OXALYL BROMIDE, 2.0M SOLUTION IN DICHLOR OMETHANE
  • Dibromoethanedione
CAS:
15219-34-8
MF:
C2Br2O2
MW:
215.83
EINECS:
239-271-7
Product Categories:
  • Others
  • Oxidation
  • Synthetic Reagents
Mol File:
15219-34-8.mol
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OXALYL BROMIDE Chemical Properties

Melting point:
-19 °C (lit.)
Boiling point:
16-17 °C/10 mmHg (lit.)
Density 
1.517 g/mL at 25 °C
refractive index 
n20/D 1.522(lit.)
Flash point:
-19°C
storage temp. 
2-8°C
solubility 
Benzene (Slightly), Chloroform
form 
Liquid
color 
Clear
BRN 
1744437
Stability:
Moisture Sensitive
CAS DataBase Reference
15219-34-8
EPA Substance Registry System
Ethanedioyl dibromide (15219-34-8)
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Safety Information

Hazard Codes 
C,T
Risk Statements 
23/24/25-34-40-29-20-14-37
Safety Statements 
26-36/37/39-45-28-27
RIDADR 
UN 3265 8/PG 2
WGK Germany 
3
8-9
HazardClass 
8
PackingGroup 
II
HS Code 
29171990

MSDS

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OXALYL BROMIDE Usage And Synthesis

Chemical Properties

clear yellow to yellow-green liquid

Uses

Used in synthetic applications of carbon-substituted iminium salts
Reactant for:
Synthesis of mutasynthons added to cultures of A. pretiosum for mutasynthetic generation of ansamitocin derivatives
Oxalic acid formation from hydroxyl radical substitutions
Cyclization to produce CRF1 receptor antagonists
Preparation, optical and electrochemical studies of thiophene end capped olig(2,3-alkylthieno[3,4-b]pyrazine)
Asymmetrical synthesis of glycosyl chlorides and bromides

Uses

Leptin from rat has been used:

  • to check the effect of intranasal nerve growth factor (NGF) on NGF activity in the spinal cord of Sprague-Dawley rats
  • for validation of labelling for leptin-bearing cells of Sprague-Dawley rats
  • to study the effect of leptin on STAT3 (signal transducer and activator of transcription 3) phosphorylation in neural population of Sprague-Dawley rats
  • to study leptin response towards chemoreflex in nucleus of the solitary tract
  • in rats, to check the effect of association between leptin and neuronal nitric oxide pathway on penicillin-induced epileptiform activity

Biochem/physiol Actions

Leptin is a hormone produced primarily in adipocytes, although leptin mRNA has also been identified in placenta and fetal tissues, gastric tissue and liver. Its primary site of action appears to be on neurons in the hypothalamus that are involved in regulating energy balance, appetite, and body weight. Leptin increases the production of nitric oxide in endothelial cells and stimulates angiogenesis in vitro and in vivo.Human and mouse leptin share ~84% sequence identity.

OXALYL BROMIDESupplier

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