1-Octacosanol Chemical Properties

Melting point:

81-83°C

Boiling point:

200-250°C

Density 

0.8681 (rough estimate)

refractive index 

1.4559 (estimate)

storage temp. 

2-8°C

solubility 

Acetonitrile (Slightly, Heated), Benzene (Slightly, Heated), Chloroform (Slightly, Heated)

pka

15.20±0.10(Predicted)

form 

Crystalline Powder or Flaked Crystals

color 

White

Water Solubility 

<0.1 g/100 mL at 21.5 ºC

Merck 

14,6744

Stability:

Stable. Light-sensitive. Incompatible with strong oxidizing agents.

LogP

13.066 (est)

CAS DataBase Reference

557-61-9(CAS DataBase Reference)

NIST Chemistry Reference

Octacosanol(557-61-9)

EPA Substance Registry System

1-Octacosanol (557-61-9)

Safety Information

Hazard Codes 

Xn

Risk Statements 

20/21/22-36/37/38

Safety Statements 

22-24/25-37/39-26

WGK Germany 

-

HS Code 

29051990

MSDS

• Language:English Provider:Policosanol
• Language:English Provider:SigmaAldrich

1-Octacosanol Usage And Synthesis

Chemical Properties

white crystals or powder

Occurrence

Octacosanol is developed from wheat germ, sugar cane, or vegetable waxes.

Uses

A 28-carbon primary fatty alcohol commonly found in the epicuticular waxes of plants. It has shown protective effects against parkonsonism and due to its excellent tolerability and non-toxicity, octacosanol may be a promising agent for PD treatment.

Definition

ChEBI: A long-chain primary fatty alcohol that is octacosane in which a hydrogen attached to one of the terminal carbons is replaced by a hydroxy group.

General Description

White crystalline powder.

Air & Water Reactions

Insoluble in water.

Reactivity Profile

1-Octacosanol is an alcohol. Flammable and/or toxic gases are generated by the combination of alcohols with alkali metals, nitrides, and strong reducing agents. They react with oxoacids and carboxylic acids to form esters plus water. Oxidizing agents convert them to aldehydes or ketones. Alcohols exhibit both weak acid and weak base behavior. They may initiate the polymerization of isocyanates and epoxides.

Fire Hazard

Flash point data for 1-Octacosanol are not available; however, 1-Octacosanol is probably combustible.

Purification Methods

Recrystallise it from large volumes of Me2CO. Sublime it at 200-250o/1mm instead of distilling it. [Beilstein 2 IV 1318.]

1-Octacosanol (557-61-9)Related Product Information

• 1-Hexadecanol
• 1-Eicosanol
• Ethyl acetate
• Levulinic acid
• Lisinopril Dihydrate
• Ramipril
• Enalapril
• 1-HEXACOSANOL
• Neosperidin dihydrochalcone
• D-Pinitol
• Chrysin
• 1-Triacontanol
• flavanol
• METHYL OCTACOSANOATE
• NIGERICIN SODIUM SALT
• HENTRIACONTANOIC ACID
• POLY(MALEIC ANHYDRIDE-ALT-1-OCTADECENE)
• TRIACONTYL ACETATE