BRUSATOL Chemical Properties

Boiling point:

727.5±60.0 °C(Predicted)

Density 

1.46±0.1 g/cm3(Predicted)

storage temp. 

Store at -20°C

form 

Solid

pka

8.58±0.15(Predicted)

color 

White to off-white

CAS DataBase Reference

114420-67-6

BRUSATOL Usage And Synthesis

Physical Form

Powder

Description

Brusatol is a natural quassinoid that shows a potential therapeutic use in cancer models by the inhibition of Nuclear factor erythroid 2-related factor 2 (Nrf2) and is capable of inducing a variety of biological effects. The effects of Brusatol on oocyte meiosis has not been addressed.

Uses

Clinically, the research shows brusatol enhances the efficacy of chemotherapy by inhibiting the Nrf2-mediated defense mechanism, and it provokes a rapid and transient inhibition of Nrf2 signaling and sensitizes mammalian cells to chemical toxicity. Brusatol overcomes chemoresistance through inhibition of protein translation.

BRUSATOL(114420-67-6)Related Product Information

• 6,8-DIMETHYL-4',5,7-TRIHYDROXYFLAVANONE
• 2,4-Dihydroxyacetophenone
• Menadione
• 7,8-Dihydroxycoumarin
• Potassium pyrophosphate
• Benzothiazole
• Cyclohexane-1,2,3,4,5,6-hexol
• D-tagatose
• Azelaic acid
• [(S)-3-[[(2E)-3-(3,4-Dihydroxyphenyl)-1-oxo-2-propenyl]oxy]-2-hydroxypropyl]β-D-glucopyranoside
• regaloside F
• (E)-3-(4-Hydroxyphenyl)propenoic acid (2S)-3-(β-D-glucopyranosyloxy)-2-hydroxypropyl ester
• Pulsatilla saponin D
• Anemoside A3 Pulchinenoside A3
• regaloside K
• 3-(4-Hydroxyphenyl)propenoic acid (2R)-1-(β-D-glucopyranosyloxy)-3-hydroxypropan-2-yl ester
• regalosideG
• Brusatol