Basic information Safety Supplier Related
ChemicalBook >  Product Catalog >  API >  Nervous system drugs >  Anxiolytics >  mexazolam

mexazolam

Basic information Safety Supplier Related

mexazolam Basic information

Product Name:
mexazolam
Synonyms:
  • CS 386
  • Melex
  • Oxazolo[3,2-d][1,4]benzodiazepin-6(5H)-one, 10-chloro-11b-(2-chlorophenyl)-2,3,7,11b-tetrahydro-3-methyl- (9CI)
  • 10-Chloro-11b-(2-chlorophenyl)-2,3,7,11b-tetrahydro-3-methyloxazolo[3,2-d][1,4]benzodiazepin-6(5H)-one
  • 10-Chloro-11b-(o-chlorophenyl)-2,3,7,11b-tetrahydro-3-methyloxazolo[3,2-d][1,4]benzodiazepin-6(5H)-one
  • mexazolam
  • 10-Chloro-2,3,7,11b-tetrahydro-3-methyl-11b-(o-chlorophenyl)oxazolo[3,2-d][1,4]benzodiazepin-6(5H)-one
  • 10-chloro-11b-(2-chlorophenyl)-3-methyl-2,3,5,7-tetrahydro-[1,3]oxazolo[3,2-d][1,4]benzodiazepin-6-one
CAS:
31868-18-5
MF:
C18H16Cl2N2O2
MW:
363.24
Mol File:
31868-18-5.mol
More
Less

mexazolam Chemical Properties

Melting point:
172-175°
Boiling point:
522.2±50.0 °C(Predicted)
Density 
1.3817 (rough estimate)
refractive index 
1.6100 (estimate)
solubility 
Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
form 
Solid
pka
6.69(at 25℃)
color 
White to Off-White
More
Less

Safety Information

Toxicity
LD50 in male, female mice; male, female rats (mg/kg): 4687, 4571, 810, 4500 orally; >6000, >6000, >4000, >4000 i.p. or s.c. (Masuda)
More
Less

mexazolam Usage And Synthesis

Description

Mexazolam is a benzodiazepine anxiolytic closely related to flutazolam. It is reported to be particularly effective against psychosomatic essential hypertension, peptic ulcer, irritable colon and autonomic dystonia.

Originator

Sankyo (Japan)

Uses

Mexazolam is a benzodiazepine derivative and have been investigated for its therapeutic value in treating anxiety. Mexazolam is known to be metabolized via the CYP3A4 pathway.

Definition

ChEBI: Mexazolam is an oxazolobenzodiazepine and a hemiaminal ether.

brand name

MELEX

mexazolamSupplier

Zhejiang J&C Biological Technology Co.,Limited
Tel
+1-2135480471 +1-2135480471
Email
sales@sarms4muscle.com
Dideu Industries Group Limited
Tel
+86-29-89586680 +86-15129568250
Email
1026@dideu.com
Energy Chemical
Tel
021-58432009 400-005-6266
Email
marketing@energy-chemical.com
TargetMol Chemicals Inc.
Tel
4008200310
Email
marketing@tsbiochem.com
Baoji Didu Pharmaceutical and Chemical Co., Ltd
Tel
02961856358 15829046862
Email
1035@dideu.com