4-Amino-3,5-dichlorophenacylbromide Chemical Properties

Melting point:

142-1450C

Boiling point:

396.4±42.0 °C(Predicted)

Density 

1.764±0.06 g/cm3(Predicted)

storage temp. 

-20°C Freezer, Under Inert Atmosphere

solubility 

DMSO (Slightly), Ethyl Acetate (Slightly)

pka

-2.21±0.10(Predicted)

form 

Solid

color 

Off-White to Yellow

Stability:

Moisture Sensitive

InChI

InChI=1S/C8H6BrCl2NO/c9-3-7(13)4-1-5(10)8(12)6(11)2-4/h1-2H,3,12H2

InChIKey

ATKJJUFAWYSFID-UHFFFAOYSA-N

SMILES

C(=O)(C1=CC(Cl)=C(N)C(Cl)=C1)CBr

CAS DataBase Reference

37148-47-3

4-Amino-3,5-dichlorophenacylbromide Usage And Synthesis

Uses

4-Amino-3,5-dichlorophenacylbromide is a compound useful in organic synthesis.

Chemical Properties

Yellow Solid

Uses

1-(4-Amino-3,5-dichlorophenyl)-2-bromoethanone Hydrobromide is an intermediate in synthesizing Clenproperol-d7 (C573002). A labelled related drug of Clenbuterol (C569998), a β-agonist which can be used as a growth promoter in farm animals.

Uses

4-Amino-3,5-dichloro-alpha-bromoacetophenone is an impurity reference for Clenbuterol and can be used as a reference substance to analyze drug quality. It is widely used in organic synthesis and drug production.

Preparation

Dissolve 4-amino-3, 5-dichloroacetophenone in chloroform and heat to 65°C. Add bromine dropwise with stirring, stir for a few minutes after adding, then add ethanol and stir. Freeze, filter out the crystals, wash with chloroform, and dry at low temperature to obtain finished products.

4-Amino-3,5-dichlorophenacylbromide(37148-47-3)Related Product Information

• 4-Aminoacetophenone
• 1-(4-amino-3,5-dichlorophenyl)-2-[(1,1-dimethylethyl)amino]ethan-1-one hydrochloride
• BROMOCLENBUTEROL
• 4-Amino-3,5-dichlorobenzaldehyde
• 1-(4-Amino-3,5-dichloro-phenyl)-2-tert-butylamino-ethanone Hydrochloride
• 4-Amino-3,5-dichloroacetophenone
• p-(2-Bromoethyl)anilineHydrochloride
• 4-Amino-3,5-dichlorophenacylbromide
• 3',5'-Dichloroacetophenone