Basic information Safety Supplier Related

cafaminol

Basic information Safety Supplier Related

cafaminol Basic information

Product Name:
cafaminol
Synonyms:
  • cafaminol
  • 3,7-Dihydro-8-[(2-hydroxyethyl)methylamino]-1,3,7-trimethyl-1H-purine-2,6-dione
  • Mecoffaminum
  • Methylcoffanolamin
  • Methylcoffanolamine
  • 1H-Purine-2,6-dione, 3,7-dihydro-8-[(2-hydroxyethyl)methylamino]-1,3,7-trimethyl-
  • Cafaminolum
  • 8-[2-hydroxyethyl(methyl)amino]-1,3,7-trimethylpurine-2,6-dione
CAS:
30924-31-3
MF:
C11H17N5O3
MW:
267.28
EINECS:
250-390-3
Mol File:
30924-31-3.mol
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cafaminol Chemical Properties

Melting point:
162-164°
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Safety Information

Toxicity
LD50 s.c. in male mice: 700 mg/kg (Klosa)
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cafaminol Usage And Synthesis

Originator

Rhinoptil,Promonta,W. Germany,1974

Definition

ChEBI: Cafaminol is an oxopurine.

Manufacturing Process

21 g 8-chlorocaffeine and 15 g beta-N-methylaminoethanol are heated to 140°-160°C for 30 minutes. Then the temperature is increased for 15-20 minutes to 165°-170°C. On cooling a colorless mass of crystals results. This is boiled with 50-60 ml ethanol and crystallized. Colorless crystals result which are soluble in water up to about 6%; pH of the aqueous solution is 6.9. The yield is 19 g while the MP is 162°-164°C.

Therapeutic Function

Nasal decongestant

cafaminolSupplier

TargetMol Chemicals Inc.
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TargetMol Chemicals Inc.
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Shaanxi Didu New Material Co., Ltd
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TargetMol Chemicals Inc.
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+8613564774135
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