cafaminol
cafaminol Basic information
- Product Name:
- cafaminol
- Synonyms:
-
- cafaminol
- 3,7-Dihydro-8-[(2-hydroxyethyl)methylamino]-1,3,7-trimethyl-1H-purine-2,6-dione
- Mecoffaminum
- Methylcoffanolamin
- Methylcoffanolamine
- 1H-Purine-2,6-dione, 3,7-dihydro-8-[(2-hydroxyethyl)methylamino]-1,3,7-trimethyl-
- Cafaminolum
- 8-[2-hydroxyethyl(methyl)amino]-1,3,7-trimethylpurine-2,6-dione
- CAS:
- 30924-31-3
- MF:
- C11H17N5O3
- MW:
- 267.28
- EINECS:
- 250-390-3
- Mol File:
- 30924-31-3.mol
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cafaminol Chemical Properties
- Melting point:
- 162-164°
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cafaminol Usage And Synthesis
Originator
Rhinoptil,Promonta,W. Germany,1974
Definition
ChEBI: Cafaminol is an oxopurine.
Manufacturing Process
21 g 8-chlorocaffeine and 15 g beta-N-methylaminoethanol are heated to 140°-160°C for 30 minutes. Then the temperature is increased for 15-20 minutes to 165°-170°C. On cooling a colorless mass of crystals results. This is boiled with 50-60 ml ethanol and crystallized. Colorless crystals result which are soluble in water up to about 6%; pH of the aqueous solution is 6.9. The yield is 19 g while the MP is 162°-164°C.
Therapeutic Function
Nasal decongestant
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cafaminol(30924-31-3)Related Product Information
- 1H-Purine-2,6-dione, 3,7-dihydro-8-(bis(2-hydroxyethyl)amino)-1,3,7-tr imethyl-
- cafaminol
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- SALOR-INT L214248-1EA
- 1,3-DIMETHYL-8-MORPHOLINO-7-(2-OXIRANYLMETHYL)-2,3,6,7-TETRAHYDRO-1H-2,6-PURINEDIONE
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- (1,3,7-TRIMETHYL-2,4-DIOXO-1,2,3,4-TETRAHYDRO-IMIDAZO[2,1-F]PURIN-8-YL)-ACETIC ACID
- 7-(3-CHLORO-2-HYDROXYPROPYL)-1,3-DIMETHYL-8-MORPHOLINO-2,3,6,7-TETRAHYDRO-1H-PURINE-2,6-DIONE
- SALOR-INT L213896-1EA
- 2,3,4,6,7,8-Hexahydro-1,3-dimethyl-8-hydroxyethyl-1H-imidazo(2,1-f)pur ine-2,4-dione