Basic information Safety Supplier Related

7-chloro-5-(2-fluorophenyl)-1,3-dihydro-3-hydroxy-1-methyl-2H-1,4-benzodiazepin-2-one

Basic information Safety Supplier Related

7-chloro-5-(2-fluorophenyl)-1,3-dihydro-3-hydroxy-1-methyl-2H-1,4-benzodiazepin-2-one Basic information

Product Name:
7-chloro-5-(2-fluorophenyl)-1,3-dihydro-3-hydroxy-1-methyl-2H-1,4-benzodiazepin-2-one
Synonyms:
  • 7-chloro-5-(2-fluoro-phenyl)-3-hydroxy-1-methyl-1,3-dihydro-benzo[e][1,4]diazepin-2-one
  • 7-chloro-5-(2-fluorophenyl)-3-hydroxy-1-methyl-3H-1,4-benzodiazepin-2-one
  • 7-chloro-5-(2-fluorophenyl)-1,3-dihydro-3-hydroxy-1-methyl-2H-1,4-benzodiazepin-2-one
  • Flutemazepam
  • SAS 646
  • 1,3-Dihydro-7-chloro-5-(2-fluorophenyl)-3-hydroxy-1-methyl-2H-1,4-benzodiazepin-2-one
  • 1-Methyl-3-hydroxy-5-(2-fluorophenyl)-7-chloro-1H-1,4-benzodiazepine-2(3H)-one
  • 2H-1,4-Benzodiazepin-2-one, 7-chloro-5-(2-fluorophenyl)-1,3-dihydro-3-hydroxy-1-methyl-
CAS:
52391-89-6
MF:
C16H12ClFN2O2
MW:
318.73
EINECS:
257-892-1
Mol File:
52391-89-6.mol
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7-chloro-5-(2-fluorophenyl)-1,3-dihydro-3-hydroxy-1-methyl-2H-1,4-benzodiazepin-2-one Chemical Properties

Melting point:
162-164 °C(Solv: cyclohexane (110-82-7))
Boiling point:
550.3±50.0 °C(Predicted)
Density 
1.40±0.1 g/cm3(Predicted)
pka
11.58±0.40(Predicted)
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7-chloro-5-(2-fluorophenyl)-1,3-dihydro-3-hydroxy-1-methyl-2H-1,4-benzodiazepin-2-one Usage And Synthesis

Uses

Flutemazepam-13C,d3, is the labeled analogue of Flutemazepam (F599410), an analogue of Temazepam (T017200), that has hypnotic, sedative, amnesiac, anxiolytic, anticonvulsant and skeletal muscle relaxant properties. Flutemazepam has been shown to have similiar propertis to Temazepam, and it is found to be effective for the treatment of severe states of anxiety, panic attacks, and severe insomnia.

Definition

ChEBI: Flutemazepam is a benzodiazepine.

7-chloro-5-(2-fluorophenyl)-1,3-dihydro-3-hydroxy-1-methyl-2H-1,4-benzodiazepin-2-oneSupplier

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