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N1-(6-ethoxypyridazin-3-yl)sulphanilamide

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N1-(6-ethoxypyridazin-3-yl)sulphanilamide Basic information

Product Name:
N1-(6-ethoxypyridazin-3-yl)sulphanilamide
Synonyms:
  • Sulfaethoxypyridazine
  • 4-Amino-N-(6-ethoxy-3-pyridazinyl)benzenesulfonamide
  • 4-azanyl-N-(6-ethoxypyridazin-3-yl)benzenesulfonamide
  • Sulfaethoxypyridazine,4-Amino-N-(6-ethoxy-3-pyridazinyl)benzenesulfonamide, N1-(6-Ethoxy-3-pyridazinyl)sulfanilamide
  • N1-(6-ethoxypyridazin-3-yl)sulphanilamide
  • SULFAETHOXYPYRIDAZIN
  • 4-amino-N-(6-ethoxypyridazin-3-yl)benzenesulfonamide
  • N(1)-(6-ethoxypyridazin-3-yl)sulfanilamid
CAS:
963-14-4
MF:
C12H14N4O3S
MW:
294.33
EINECS:
213-514-7
Mol File:
963-14-4.mol
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N1-(6-ethoxypyridazin-3-yl)sulphanilamide Chemical Properties

Melting point:
182-184 °C
Boiling point:
565.9±60.0 °C(Predicted)
Density 
1.416±0.06 g/cm3(Predicted)
storage temp. 
Refrigerator
solubility 
DMSO (Slightly), Methanol (Slightly)
pka
7.24±0.30(Predicted)
form 
Solid
color 
Off-White to Light Brown
CAS DataBase Reference
963-14-4
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Safety Information

WGK Germany 
3
RTECS 
WO9410000
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N1-(6-ethoxypyridazin-3-yl)sulphanilamide Usage And Synthesis

Chemical Properties

Crystals. Soluble in water at 37?.

Uses

Sulfaethoxypyridazine is a sulfonamide that is used in veterinary medicine as feedstuffs, and in human medicines in the treatment of systematic infections.

Uses

N1-(6-ethoxypyridazin-3-yl)sulphanilamide is a sulfonamide that is used in veterinary medicine as feedstuffs, and in human medicines in the treatment of systematic infections.

Definition

ChEBI: Sulfaethoxypyridazine is a sulfonamide consisting of 6-ethoxypyridazine with a 4-aminobenzenesulfonamido group at the 3-position. Generally licensed for veterinary use only against bacterial infections, such as fowl cholera and salmonella infection. It has a role as an antibacterial agent.

Safety Profile

When heated to decomposition it emits acrid smoke and irritating fumes.

in vivo

Feeding of Sulfaethoxypyridazine, a long-acting sulfonamide, to rats at dietary levels of 800, 1600, and 3200 ppm resulted in the development of characteristic lens opacities by 23 weeks. Daily oral administration of 30, 67, and 150 mg/kg to dogs resulted in the development of similar cataracts by 14 weeks[1].

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