(R)-2-Amino-2-(4-fluorophenyl)ethanol Chemical Properties

Boiling point:

287.4±25.0 °C(Predicted)

Density 

1.208±0.06 g/cm3(Predicted)

storage temp. 

2-8°C(protect from light)

pka

12.48±0.10(Predicted)

Safety Information

HS Code 

2922190090

(R)-2-Amino-2-(4-fluorophenyl)ethanol Usage And Synthesis

Chemical Properties

(R)-2-Amino-2-(4-fluorophenyl)ethanol is a white solid.

Uses

(R)-2-Amino-2-(4-fluorophenyl)ethanol is used for synthesis of organic compounds.

Hazard

H302: Harmful if swallowed.
H315: Causes skin irritation.
H319: Causes serious eye irritation.
H335: May cause respiratory irritation.

Synthesis

To a stirred solution of lithium aluminium hydride (1.0 M in THF, 11.9 ml, 11.9 mmol) at 0℃ was added 4- (R)-fluorophenylglycine (1.0 g, 5.9 mmol) portion wise over 1 hour. The mixture was stirred at room temperature for 16 hours. Water (0.45 ml), 4 NNaOH (0.45 ml) and water (1.34 ml) was added to the mixture and the mixture was stirred for 10 minutes before being filtered. The filtrate was concentrated to give a yellow residue, (R)-2-Amino-2-(4-fluorophenyl)ethanol.

(R)-2-Amino-2-(4-fluorophenyl)ethanol(174770-74-2)Related Product Information

• Ethanol