Venturicidin
Venturicidin Basic information
- Product Name:
- Venturicidin
- Synonyms:
-
- AaboMycin A2
- Venturicidin
- 4,21-Dioxabicyclo[15.3.1]heneicosa-9,15,18-trien-3-one, 11-[(2,6-dideoxy-β-D-arabino-hexopyranosyl)oxy]-1-hydroxy-5-[(1R,3R,4S,5S)-4-hydroxy-1,3,5-trimethyl-6-oxooctyl]-6,8,16,18-tetramethyl-, (1R,5S,6R,8R,9E,11R,15E,17R)-
- (1R,2E,7R,8E,10R,12R,13S,17R)-7-[(2R,4R,6R)-4,5-dihydroxy-6-methyloxan-2-yl]oxy-17-hydroxy-13-[(2R,4R,5S,6S)-5-hydroxy-4,6-dimethyl-7-oxononan-2-yl]-2,10,12,20-tetramethyl-14,21-dioxabicyclo[15.3.1]henicosa-2,8,19-trien-15-one
- CAS:
- 33538-72-6
- MF:
- C40H66O10
- MW:
- 706.95
- Mol File:
- 33538-72-6.mol
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Venturicidin Chemical Properties
- Melting point:
- 168-170°; mp 145-149° (ethyl acetate-petr ether)
- alpha
- D +100° (c = 0.847 in chloroform)
- Boiling point:
- 823.4±65.0 °C(Predicted)
- Density
- 1.14±0.1 g/cm3(Predicted)
- solubility
- DMF: Soluble; DMSO: Soluble; Ethanol: Soluble; Methanol: Soluble
- pka
- 11.80±0.70(Predicted)
- form
- White to off-white solid.
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Venturicidin Usage And Synthesis
Description
Venturicidin B is a macrolide bacterial metabolite that has been found in Streptomyces.
Uses
The macrolide antibiotic Venturicidin B, isolated from a Streptomyces sp., is a potent inhibitor of mitochondrial ATP synthase complex acting on the F0 membrane sector. Venturicidin A was originally isolated as an antifungal agent.
Uses
Venturicidin B is a potent inhibitor of mitochondrial ATP synthase complex acting on the F0 membrane sector.
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