Solamargine
Solamargine Basic information
- Product Name:
- Solamargine
- Synonyms:
-
- SOLAMERGINE
- Solamargine, >98%
- Solamargine 20311-51-7
- δ-Solanigrine
- 2)-O-[6-deoxy-a-L-Mannopyranosyl-(1®
- b-D-Glucopyranoside, (3b,22a,25R)-spirosol-5-en-3-yl O-6-deoxy-a-L-Mannopyranosyl-(1®
- (3β,22α,25R)-Spirosol-5-en-3-yl 6-deoxy-α-L-mannopyranosyl-(1→2)-[6-deoxy-α-L-mannopyranosyl-(1→4)]-β-D-glucopyranoside
- [(22R,25R)-Spirosola-5-ene-3β-yl]2-O,4-O-bis(6-deoxy-α-L-mannopyranosyl)-β-D-glucopyranoside
- CAS:
- 20311-51-7
- MF:
- C45H73NO15
- MW:
- 868.06
- Product Categories:
-
- chemical reagent
- pharmaceutical intermediate
- phytochemical
- reference standards from Chinese medicinal herbs (TCM).
- standardized herbal extract
- Alkaloids
- Mol File:
- 20311-51-7.mol
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Solamargine Chemical Properties
- Melting point:
- 301 °C
- Density
- 1.38
- storage temp.
- Refrigerator
- solubility
- DMSO (Slightly), Methanol (Slightly)
- form
- Solid
- pka
- 12?+-.0.70(Predicted)
- color
- Light Beige
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Solamargine Usage And Synthesis
Chemical Properties
White crystalline powder, soluble in organic solvents such as methanol, ethanol, and DMSO. It is derived from the fruit of Solanum aviculare Forst.
Uses
α-Solamargine is a steroidal glycosyl-alkaloid which displays inactivation of PI3-L/Akt and reduction for SP1 and p65 in the suppression of human lung cancer cells.
Definition
ChEBI: Solamargine is an azaspiro compound, a steroid and an oxaspiro compound.
in vivo
Solamargine (10 mg/kg; intragastric administration; once daily for 8 days) exhibits an antitumor effect and promotes the apoptosis of GC in vivo[4].
| Animal Model: | Female specific pathogen-free BALB/c nude mice weighing 18-20 g (6-8-weeks-old)[4] |
| Dosage: | 10 mg/kg |
| Administration: | Intragastric administration; once daily for 8 days |
| Result: | Tumor growth was significantly inhibited . |
SolamargineSupplier
Chembest Research Laboratories Limited
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- +86-21-20908456
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Nanjing Chemlin Chemical Co., Ltd
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- 025-83697070
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Sichuan Kulinan Technology Co., Ltd
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- 400-1166-196 18981987031
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Shenzhen Sungening Bio-Tech Co., Ltd
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- +86-0755-89668383
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Dalian Meilun Biotech Co., Ltd.
- Tel
- 0411-62910999 13889544652
- sales@meilune.com