Methanesulfonic anhydride Chemical Properties

Melting point:

64-67 °C (lit.)

Boiling point:

125 °C/4 mmHg (lit.)

Density 

1,36 g/cm³

vapor density 

3.3 (vs air)

refractive index 

1.5300 (estimate)

Flash point:

125°C/4mm

storage temp. 

Store at <= 20°C.

solubility 

Soluble in organic solvents.

form 

Powder, Crystals and/or Chunks

color 

White to light brown to gray

Sensitive 

Moisture Sensitive

BRN 

972316

InChIKey

IZDROVVXIHRYMH-UHFFFAOYSA-N

CAS DataBase Reference

7143-01-3(CAS DataBase Reference)

NIST Chemistry Reference

Methanesulfonic anhydride(7143-01-3)

EPA Substance Registry System

Methanesulfonic acid, anhydride (7143-01-3)

Safety Information

Hazard Codes 

C

Risk Statements 

14-35

Safety Statements 

26-36/37/39-45

RIDADR 

UN 3261 8/PG 2

WGK Germany 

3

F 

3-10

TSCA 

Yes

HazardClass 

8

PackingGroup 

III

HS Code 

29041000

MSDS

• Language:English Provider:Methanesulfonic anhydride
• Language:English Provider:SigmaAldrich
• Language:English Provider:ALFA

Methanesulfonic anhydride Usage And Synthesis

Chemical Properties

white to light brown to grey powder, crystals and/

Uses

Methanesulfonic anhydride is used to prepare methylsulfonyl esters called as mesylates. It finds application in the reaction of aromatic alkylation. It reacts with dimethylsulfoxide to get sulfoxonium complex, which is a useful oxidizing agent.

Preparation

Methanesulfonic anhydride may be prepared by the dehydration of methanesulfonic acid with phosphorus pentoxide.
P2O5 + 6 CH3SO3H → 3 (CH3SO2)2O + 2 H3PO4
Methanesulfonic anhydride can be purified by distillation under vacuum (distillation of a solid) or by recrystallized from Methyl tert-butyl ether/toluene.

Safety

Not only is Methanesulfonic anhydride corrosive, posing potential risks to skin, eyes, and mucous membranes, but it is also sensitive to moisture. As a hygroscopic substance, exposure to water can lead to degradation, compromising its efficacy and safety. Therefore, meticulous storage conditions are paramount to ensure the stability of the compound. To safeguard the integrity of methanesulfonic anhydride, storing it in a cool and dry environment is recommended. The storage facility should be adequately ventilated to prevent the accumulation of vapors and maintain optimal conditions for the compound. Furthermore, the storage containers must be tightly sealed to prevent moisture ingress and subsequent degradation.

Methanesulfonic anhydride (7143-01-3)Related Product Information

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