CARBOXYPEPTIDASE W Chemical Properties

storage temp. 

−20°C

form 

powder

color 

white

Water Solubility 

Soluble in water.

Specific Activity

≥50units/mg protein

Safety Information

Hazard Codes 

Xn

Risk Statements 

36/37/38-42

Safety Statements 

22-24-26-36/37-45

WGK Germany 

1

F 

10-21

MSDS

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CARBOXYPEPTIDASE W Usage And Synthesis

Uses

Carboxypeptidase Y from yeast is used for C-terminal sequencing of proteins. Also for C-terminal modification of proteins and peptides. Due to its amidase action, it is applied to the sequence analysis of peptides having amidated COOH-terminal groups such as oxytocin and vasopressin.

Biological Activity

The glycoprotein has a molecular weight of about 61,000, has a nitrogen content of 12.74%. It is a single polypeptide chain of 442 residues with 16 residues of glucosamine in the carbohydrate moiety. Lysine is at the NH2 terminus and -Asp-Ser-Thr-Leu is the COOH-terminal sequence. The principal action of the enzyme is to remove COOH-terminal residues from polypeptide chains. It is used as a vacuolar marker enzyme for studies on protein transport and localization.

CARBOXYPEPTIDASE W(9046-67-7)Related Product Information

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