Basic information Safety Supplier Related

FUMONISIN B3

Basic information Safety Supplier Related

FUMONISIN B3 Basic information

Product Name:
FUMONISIN B3
Synonyms:
  • FUMONISIN B3
  • Fumonisin B3 from Fusarium moniliforme
  • 1,2,3-Propanetricarboxylic acid, 1,1'-[(1S,2R)-1-[(2S,4R,11S,12S)-12-amino-4,11-dihydroxy-2-methyltridecyl]-2-[(1R)-1-methylpentyl]-1,2-ethanediyl] ester, (2R,2'R)-
  • Fumonisin B3 solution in Methanol, 10μg/mL
  • Fumonisin B3 (FB3)
  • Fumonisin B3 (>90%)
CAS:
1422359-85-0
MF:
C34H59NO14
MW:
705.83
Mol File:
Mol File
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FUMONISIN B3 Chemical Properties

Boiling point:
867.0±65.0 °C(Predicted)
Density 
1.222±0.06 g/cm3(Predicted)
storage temp. 
Store at -20°C
solubility 
DMSO (Very Slightly), Methanol (Slightly)
form 
A powder
pka
3?+-.0.23(Predicted)
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Safety Information

HS Code 
2932209090
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FUMONISIN B3 Usage And Synthesis

Description

Fumonisin B3 (FB3) is a mycotoxin that has been found in Fusarium. It is cytotoxic to primary rat hepatocytes when used at concentrations of 125, 250, and 500 μM. Dietary administration of FB3 (0.05%) for 14 or 21 days induces hepatocyte nodules, a marker of cancer initiation, in rats. FB3 has been detected in corn and corn-based foods and livestock feeds.

Uses

Fumonisin B3 is a mycotoxin present in corn. Fungal metabolite believed to cause leukoencephalomalacia in horses.

References

[1] J. RHEEDER H V W Marasas. Production of Fumonisin Analogs by Fusarium Species[J]. Applied and Environmental Microbiology, 2002, 68 1: 2101-2105. DOI: 10.1128/aem.68.5.2101-2105.2002
[2] W.C.A. GELDERBLOM . Structure-activity relationships of fumonisins in short-term carcinogenesis and cytotoxicity assays[J]. Food and Chemical Toxicology, 1993, 31 6: Pages 407-414. DOI: 10.1016/0278-6915(93)90155-r
[3] BULLERMAN L B. Occurrence of Fusarium and fumonisins on food grains and in foods.[J]. Advances in experimental medicine and biology, 1996, 392: 27-38. DOI: 10.1007/978-1-4899-1379-1_3

FUMONISIN B3Supplier

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