Ethylenediaminetetraacetic acid tetrasodium salt dihydrate Chemical Properties

Melting point:

>300°C

Flash point:

350°C

storage temp. 

room temp

solubility 

H₂O: clear, colorless

form 

Liquid

color 

Yellow-Orange

PH

10.5-11.5 (50g/l, H2O, 20℃)

Water Solubility 

almost transparency

BRN 

3861753

CAS DataBase Reference

10378-23-1(CAS DataBase Reference)

Safety Information

Hazard Codes 

Xi,Xn

Risk Statements 

36/37/38-41-22

Safety Statements 

26-36/37-46-39

WGK Germany 

3

RTECS 

DB6145180

TSCA 

Yes

HS Code 

29224995

MSDS

• Language:English Provider:ACROS
• Language:English Provider:SigmaAldrich
• Language:English Provider:ALFA

Ethylenediaminetetraacetic acid tetrasodium salt dihydrate Usage And Synthesis

Chemical Properties

white crystals or powder

Uses

Ethylenediaminetetraacetic acid tetrasodium salt dihydrate has been used:

• as a chelating agent to isolate human endometrial stem cell/stromal cells (hEnSCs) from menstrual blood
• as a chelator in animal and testicular cell isolation
• as a chelator for the culture of neural stem cells

Uses

Used to eliminate enzyme inhibition by traces of heavy metals, and to inhibit enzymes that require divalent cations as cofactors.

General Description

Ethylenediaminetetraacetic acid (EDTA) is a chelator of metal ions. It is a substituted diamine, which has antibacterial activity. EDTA removes the undesirable effects of ferric, cupric and manganic ions in bleaching. It prevents cellular division, chlorophyll synthesis and algal biomass production. EDTA is an inhibitor of metalloprotease. It has anticoagulant property.

reaction suitability

reagent type: chelator

Biological Activity

Ethylenediaminetetraacetic acid (EDTA) is used to eliminate enzyme inhibition by traces of heavy metals, and to inhibit enzymes th at require divalent cations as cofactors.', 'Ethylenediaminetetraacetic acid (EDTA) is used to tre at patients poisoned with heavy metal ions. It functions as a chelator of the zinc ion in the active site of metalloproteases. EDTA inhibits other metal ion-dependent proteases such as calcium-dependent cysteine proteases. It might interfere with biological events which are metal ion-dependent. EDTA inhibits platelet aggregation and is the most preferred anticoagulant for platelet counts. It associates with other active agents to modulate microorganisms and biofilms, like citric acid, alcohol, antibiotics, polyhexamethylene biguanide (PHMB) quaternary ammonium compounds, and other antiseptics. EDTA is used as an anticoagulant for hematological testing, as it preserves the cellular components and morphology of blood cells. 

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