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Ethyl 3-benzoylacrylate

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Ethyl 3-benzoylacrylate Basic information

Product Name:
Ethyl 3-benzoylacrylate
Synonyms:
  • Ethyl 3-benzoylacrylate, HPLC 92%
  • 3-Benzoyl Acrylic Acid Ethyl Ester
  • ETHYL 3-BENZOYLACRYLATE, TECH., 92%
  • ethyl e-benzoylacrylate
  • trans-3-Benzoylacrylicacidethylester~Ethyltrans-4-oxo-4-phenyl-2-butenoate
  • Enalapril Impurity 7
  • Ethyl 3-benzoylacrylate, tech., containing ca. 3% cis-isomer, 93%
  • E3BA
CAS:
17450-56-5
MF:
C12H12O3
MW:
204.22
EINECS:
621-286-9
Product Categories:
  • Aromatic Aldehydes & Derivatives (substituted)
  • C12 to C63
  • Pharmaceutical Intermediates
  • Carbonyl Compounds
  • Esters
Mol File:
17450-56-5.mol
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Ethyl 3-benzoylacrylate Chemical Properties

Melting point:
32 °C
Boiling point:
184-185 °C/25 mmHg (lit.)
Density 
1.112 g/mL at 25 °C (lit.)
refractive index 
1.542-1.546
Flash point:
88°C
storage temp. 
Sealed in dry,Room Temperature
Specific Gravity
1.112
BRN 
2210035
InChIKey
ACXLBHHUHSJENU-HJWRWDBZSA-N
CAS DataBase Reference
17450-56-5(CAS DataBase Reference)
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Safety Information

Hazard Codes 
Xi,Xn
Risk Statements 
36/37/38-22
Safety Statements 
24/25-37/39-26-36
RIDADR 
UN2810
WGK Germany 
3
HazardClass 
6.1
PackingGroup 
III
HS Code 
29183000

MSDS

  • Language:English Provider:ACROS
  • Language:English Provider:ALFA
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Ethyl 3-benzoylacrylate Usage And Synthesis

Chemical Properties

clear yellow liquid

Uses

Ethyl 3-benzoylacrylate is an impurity of Enalapril (E555250), an?antihypertensive and an angiotensin-converting enzyme (ACE) inhibitor.

Synthesis Reference(s)

Tetrahedron Letters, 13, p. 407, 1972 DOI: 10.1016/S0040-4039(01)84337-9

General Description

Ethyl 3-benzoylacrylate (ethyl trans-3-benzoylacrylate) undergoes enantioselective guanidine catalyst promoted Michael addition reaction with dithranol to yield Michael adduct.

Ethyl 3-benzoylacrylate Preparation Products And Raw materials

Preparation Products

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