5-O-Desmethyl Donepezil Chemical Properties

Melting point:

170-172°C

Boiling point:

545.3±50.0 °C(Predicted)

Density 

1.190±0.06 g/cm3(Predicted)

storage temp. 

-20°C Freezer

solubility 

Chloroform (Slightly), DMSO (Slightly), Ethyl Acetate (Slightly, Heated)

form 

Solid

pka

8.16±0.40(Predicted)

color 

White to Pale Brown

CAS DataBase Reference

120013-57-2

5-O-Desmethyl Donepezil Usage And Synthesis

Chemical Properties

Off-White Solid

Uses

A metabolite of Donepezil, an inhibitor of acetylcholinesterase

Uses

A metabolite of Donepezil (D531750), an inhibitor of acetylcholinesterase.

Definition

ChEBI: 5-O-desmethyldonepezil is a member of the class of piperidines that is donepezil in which the 5-methoxy group has been demethylated to the corresponding hydroxy derivative. It is metabolite of donepezil, a drug used in the treatment of dementia. It has a role as a drug metabolite. It is a member of piperidines, a cyclic ketone, an aromatic ether and a member of guaiacols.

5-O-Desmethyl Donepezil(120013-57-2)Related Product Information

• Donepezil Hydrochloride
• Donepezil
• Donepezil Impurity 17 HCl
• 1-Benzyl-4-(5,6-dimethoxy-1-oxoindan-2-ylindenemethyl)piperidine
• 2-[(1-Benzylpiperidin-4-yl)hydroxyMethyl]-5,6-diMethoxyindan-1-one
• RAC (CIS/TRANS) DONEPEZIL N-OXIDE
• XWAIAVWHZJNZQQ-RPXFAUAJSA-N
• 2-[(E)-(1-BENZYL-4-PIPERIDINYL)METHYLIDENE]-5,6-DIMETHOXY-1-INDANONE
• 3,5-Dichloro-4-hydroxypyridine
• Donepezil Impurity
• 6-O-Desmethyl Donepezil β-D-Glucuronide
• 2-isonicotinoyl-5,6-diMethoxy-2,3-dihydro-1H-inden-1-one
• 5,6-DIMETHOXY-2-PYRIDIN-4-YLMETHYL-INDAN-1-ONE
• 5,6-Dimethoxy-1-indanone
• 4-PYRIDINECARBOXALDEHYDE N-OXIDE
• Donepezil Impurity 8
• 5,6-Dimethoxy-2-(pyridine-4-yl)methylene-indan-1-one
• Dihydro Donepezil (Mixture of Diastereomers)