Basic information Safety Supplier Related

Metoprolol Acid

Basic information Safety Supplier Related

Metoprolol Acid Basic information

Product Name:
Metoprolol Acid
Synonyms:
  • H 117/04
  • 4-[2-Hydroxy-3-[(1-methylethyl)amino]propoxy]-benzeneacetic Acid
  • Atenolol Acid
  • Metoprolol Acid
  • SL 77-010
  • Atenolol IMpurity –G(EP)
  • Atenolol Related CoMpound C
  • 4-(3-Isopropylamino-2-hydroxypropoxy)benzeneacetic acid
CAS:
56392-14-4
MF:
C14H21NO4
MW:
267.32
Product Categories:
  • Intermediates & Fine Chemicals
  • Metabolites & Impurities
  • Pharmaceuticals
Mol File:
56392-14-4.mol
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Metoprolol Acid Chemical Properties

Melting point:
174-176°C
Boiling point:
477.1±40.0 °C(Predicted)
Density 
1.159±0.06 g/cm3(Predicted)
storage temp. 
-20°C
solubility 
DMSO (Slightly), Methanol (Slightly, Heated), Water (Slightly)
form 
Solid
pka
4.41±0.10(Predicted)
color 
White to Off-White
Stability:
Hygroscopic
CAS DataBase Reference
56392-14-4
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Safety Information

Hazard Codes 
Xn
Risk Statements 
22
WGK Germany 
3
RTECS 
CY1634360
Toxicity
LD50 intravenous in dog: > 500mg/kg
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Metoprolol Acid Usage And Synthesis

Chemical Properties

Off-white Solid

Uses

The acidic inactive metabolite of Metoprolol

Uses

4-(2-Hydroxy-3-isopropylaminopropoxy)phenylacetic acid may be used as an analytical standard for the determination of the analyte in environmental water samples, wastewater samples, and human and animal biological samples by various chromatography techniques.

Definition

ChEBI: A monocarboxylic acid that is phenylacetic acid substituted by a 2-hydroxy-3-(propan-2-ylamino)propoxy group at position 4. It is a metabolite of the drug atenolol.

General Description

4-(2-Hydroxy-3-isopropylaminopropoxy)phenylacetic acid is a metabolite of the selective β-1 blocker drug metoprolol.

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