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N-Desethyl Vardenafil

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N-Desethyl Vardenafil Basic information

Product Name:
N-Desethyl Vardenafil
Synonyms:
  • 1-[[3-(1,4-Dihydro-5-methyl-4-oxo-7-propylimidazo[5,1-f][1,2,4]triazin-2-yl)-4-ethoxyphenyl]sulfonyl]-piperazine
  • Vardenafil Impurity 4(Vardenafil N-Desethyl Impurity)
  • 2-(2-ethoxy-5-(piperazin-1-ylsulfonyl)phenyl)-5-methyl-7-propylimidazo[5,1-f][1,2,4]triazin-4(3H)-one
  • Vardenafil N-Desethyl Impurity
  • Vardenafil N-Desethyl Imp
  • N-Desethyl Vardenafil Impurity
  • 2-(2-ethoxy-5-piperazin-1-ylsulfonylphenyl)-5-methyl-7-propyl-1H-imidazo[5,1-f][1,2,4]triazin-4-one
  • 2-(2-Ethoxy-5-(piperazin-1-ylsulfonyl)phenyl)-5-methyl-7-propylimidazo[5,1-f][1,2,4]triazin-4(1H)-one
CAS:
448184-46-1
MF:
C21H28N6O4S
MW:
460.55
Product Categories:
  • Metabolites & Impurities, Pharmaceuticals, Intermediates & Fine Chemicals
  • Various Metabolites and Impurities
  • Intermediates & Fine Chemicals
  • Metabolites & Impurities
  • Pharmaceuticals
Mol File:
448184-46-1.mol
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N-Desethyl Vardenafil Chemical Properties

Boiling point:
699.8±65.0 °C(Predicted)
Density 
1.44±0.1 g/cm3(Predicted)
storage temp. 
-20°C Freezer, Under Inert Atmosphere
solubility 
DMF: 30mg/mL; DMSO: 30 mg/mL; Ethanol: 30 mg/mL; Ethanol:PBS (pH 7.2) (1:4): 0.2 mg/mL
form 
A crystalline solid
pka
7.73±0.10(Predicted)
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N-Desethyl Vardenafil Usage And Synthesis

Description

N-Desethyl vardenafil is a metabolite of vardenafil , a phosphodiesterase 5 inhibitor, that is formed by the action of cytochrome P450 (CYP)3A4 and CYP3A5.

Chemical Properties

White to Off-White Solid

Uses

N-Desethyl Vardenafil is a metabolite of Vardenafil, a phosphodiesterase 5 inhibitor.

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