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Cefetrizole

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Cefetrizole Basic information

Product Name:
Cefetrizole
Synonyms:
  • Cefetrizole
  • (6R,7R)-8-Oxo-7-[2-thienylacetylamino]-3-[(1H-s-triazol-3-ylthio)methyl]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
  • 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 8-oxo-7-[[2-(2-thienyl)acetyl]amino]-3-[(1H-1,2,4-triazol-5-ylthio)methyl]-, (6R,7R)-
CAS:
65307-12-2
MF:
C16H15N5O4S3
MW:
437.52
Mol File:
65307-12-2.mol
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Cefetrizole Chemical Properties

Density 
1.71±0.1 g/cm3(Predicted)
pka
2.65±0.50(Predicted)
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Cefetrizole Usage And Synthesis

Biological Activity

Ceftezole is an α-Glucosidase inhibitor with IC50 and Ki values of 2.1 μM and 0.578 μM, respectively.

in vitro

In in vitro α-Glucosidase assays, Ceftezole is shown to be a reversible, non-competitive inhibitor of yeast α-glucosidase with a K i value of 5.78×10 -7 M when the enzyme mixture is pretreated with ceftezole.

target

IC50: 2.1 μM (α-Glucosidase)
Ki: 0.578 μM (α-Glucosidase)

CefetrizoleSupplier

MedChemexpress LLC
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TargetMol Chemicals Inc.
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Hangzhou changru chemical co., ltd
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Beijing Jin Ming Biotechnology Co., Ltd.
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TargetMol Chemicals Inc.
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4008200310
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marketing@tsbiochem.com
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Cefetrizole(65307-12-2)Related Product Information