Irloxacin
Irloxacin Basic information
- Product Name:
- Irloxacin
- Synonyms:
-
- Irloxacin
- pirfloxacin
- 1-Ethyl-6-fluoro-1,4-dihydro-4-oxo-7-(1H-pyrrol-1-yl)-3-quinolinecarboxylic acid
- 1-Ethyl-6-fluoro-1,4-dihydro-4-oxo-7-(1H-pyrrol-1-yl)quinoline-3-carboxylic acid
- E-3432
- Irloxacin USP/EP/BP
- Inhibitor,acid pH,antibacterial agent,Bacterial,gram-positive,oral,Irloxacin,Pirfloxacin,gram-negative bacteria,inhibit
- 3-Quinolinecarboxylic acid, 1-ethyl-6-fluoro-1,4-dihydro-4-oxo-7-(1H-pyrrol-1-yl)-
- CAS:
- 91524-15-1
- MF:
- C16H13FN2O3
- MW:
- 300.28
- Mol File:
- 91524-15-1.mol
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Irloxacin Chemical Properties
- Melting point:
- 252-255 °C(Solv: N,N-dimethylformamide (68-12-2))
- Boiling point:
- 495.9±45.0 °C(Predicted)
- Density
- 1.36±0.1 g/cm3(Predicted)
- storage temp.
- Store at -20°C
- solubility
- DMSO:0.0(Max Conc. mg/mL);0.0(Max Conc. mM)
- pka
- -0.07±0.20(Predicted)
- form
- Solid
- color
- White to off-white
- CAS DataBase Reference
- 91524-15-1
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Irloxacin Usage And Synthesis
Uses
Irloxacin (Pirfloxacin) is a quinolone antibacterial agent. Irloxacin shows greater activity with an acid pH. Irloxacin has a good in vitro antimicrobial spectrum against both gram-positive and gram-negative bacteria. Orally active[1].
Hazard
Low toxicity by ingestion.
References
[1] Casal M, et al. Preliminary study of the in vitro activity of irloxacin against mycobacteria. Chemotherapy. 1995;41(3):204-207. DOI:10.1159/000239345
[2] Guzmán A, et al. Acute and subchronic toxicity studies of the new quinolone antibacterial agent irloxacin in rodents. Arzneimittelforschung. 1999;49(5):448-456. DOI:10.1055/s-0031-1300441
IrloxacinSupplier
TargetMol Chemicals Inc.
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