Naxagolide Chemical Properties

storage temp. 

Store at -20°C

solubility 

DMSO : 200 mg/mL (808.64 mM; Need ultrasonic)

form 

Solid

color 

White to off-white

Naxagolide Usage And Synthesis

Uses

Antiparkinsonian;dopamine agonist.

Definition

ChEBI: Naxagolide is an organic heterotricyclic compound that is (4aR,10bR)-3,4,4a,5,6,10b-hexahydro-2H-naphtho[1,2-b][1,4]oxazine substituted by propyl and hydroxy groups at positions 4 and 9, respectively. It is a potent dopamine D2-receptor agonist and its hydrochloride salt was under clinical development by Merck & Co as a potential antiparkinsonian agent (now discontinued). It has a role as an antiparkinson drug, a dopamine agonist and an anticonvulsant. It is a tertiary amino compound, an organic heterotricyclic compound and a member of phenols. It is a conjugate base of a naxagolide(1+).

Naxagolide(88058-88-2)Related Product Information

• 3-PROPYLMORPHOLINE
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• 2-O-TOLYL-MORPHOLINE
• (S)-4-(3-AMINO-BUTYL)-PHENOL
• Phenylephrine hydrochloride
• (-)-Pseudoephedrine
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• (1R,2R)-(-)-N-METHYLPSEUDOEPHEDRINE
• 3-Ethylmorpholine hydrochloride
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• (R)-3-Methylmorpholine
• Naxagolide