Decursinol Chemical Properties

Melting point:

178 °C

Boiling point:

433.6±45.0 °C(Predicted)

Density 

1.293±0.06 g/cm3(Predicted)

storage temp. 

4°C, protect from light

solubility 

DMF: 30 mg/ml; DMSO: 15 mg/ml; Ethanol: slightly soluble

form 

A solid

pka

13.87±0.40(Predicted)

color 

White to off-white

CAS DataBase Reference

23458-02-8

Decursinol Usage And Synthesis

Uses

Decursinol, isolated from the roots of Angelica gigas, possesses antinociceptive effect with orally bioavailability. Decursinol possesses anti-tumor and anti-metastasis activity[1].

Definition

ChEBI: An organic heterotricyclic compound that is 7,8-dihydro-2H,6H-pyrano[3,2-g]chromen-2-one substituted by a beta-hydroxy group at position 7 and two methyl groups at position 8. It is isolat d from the roots of Angelica gigas and has been found to possess significant inhibitory activity against acetylcholinesterase enzyme (EC 3.1.1.7).

References

[1] Choi SS, et al. Antinociceptive mechanisms of orally administered decursinol in the mouse. Life Sci. 2003 Jun 13;73(4):471-85. DOI:10.1016/s0024-3205(03)00311-4
[2] Son SH, et al. Decursin and decursinol from Angelica gigas inhibit the lung metastasis of murine colon carcinoma. Phytother Res. 2011 Jul;25(7):959-64. DOI:10.1002/ptr.3372

Decursinol(23458-02-8)Related Product Information

• NODAKENETIN
• Nodakenin
• ANGELIC ACID
• 5,7-Dihydroxy-4-methylcoumarin
• Angelicide
• ISOBERGAPTOL
• 4-Hydroxycoumarin
• 4-METHYLESCULETIN
• 6-ISOPENTENYLOXYISOBERGAPTEN
• 5-Hydroxyxanthotoxin
• MEDICAGOL
• WEDELOLACTONE
• 5,8-DIHYDROXYPSORALEN
• pimpinellin
• Isoimperatorin
• Decursin
• Decuroside I
• Decursitin D