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(R)-Amlodipine

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(R)-Amlodipine Basic information

Product Name:
(R)-Amlodipine
Synonyms:
  • 3-O-ethyl 5-O-methyl (4R)-2-(2-aminoethoxymethyl)-4-(2-chlorophenyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylate
  • Amlodipine Impurity 15(R-Isomer)
  • d-Amlodipine,(R)-(+)-Amlodipine
  • (R)-(+)-Amlodipine
  • (R)-Amlodipine
  • 3,5-Pyridinedicarboxylic acid, 2-[(2-aminoethoxy)methyl]-4-(2-chlorophenyl)-1,4-dihydro-6-methyl-, 3-ethyl 5-methyl ester, (4R)-
  • 3,5-Pyridinedicarboxylic acid, 2-[(2-aminoethoxy)methyl]-4-(2-chlorophenyl)-1,4-dihydro-6-methyl-, 3-ethyl 5-methyl ester, (R)-
  • d-Amlodipine
CAS:
103129-81-3
MF:
C20H25ClN2O5
MW:
408.88
Product Categories:
  • Amines
  • Chiral Reagents
  • Dihydropyridine
  • Heterocycles
  • Intermediates & Fine Chemicals
  • Pharmaceuticals
Mol File:
103129-81-3.mol
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(R)-Amlodipine Chemical Properties

Melting point:
101-103°C
Boiling point:
527.2±50.0 °C(Predicted)
Density 
1.227±0.06 g/cm3(Predicted)
storage temp. 
-20°C Freezer
solubility 
Acetonitrile (Slightly), Chloroform (Slightly), Methanol (Slightly)
form 
Solid
pka
8.97±0.10(Predicted)
color 
White to Off-White
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(R)-Amlodipine Usage And Synthesis

Chemical Properties

White Solid

Uses

(R)-Enantiomer of Amlodipine. A dihydropyridine calcium channel blocker; activity resides mainly in the (-)-isomer.

Uses

(R)-Enantiomer of Amlodipine (A633495). A dihydropyridine calcium channel blocker; activity resides mainly in the (-)-isomer.

Definition

ChEBI: (R)-amlodipine is the (4R)-enantiomer of amlodipine. It is an enantiomer of a (S)-amlodipine.

(R)-AmlodipineSupplier

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