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SCE 2174

Basic information Safety Supplier Related

SCE 2174 Basic information

Product Name:
SCE 2174
Synonyms:
  • 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-[[(2-amino-4-thiazolyl)acetyl]amino]-3-[[[1-[2-(dimethylamino)ethyl]-1H-tetrazol-5-yl]thio]methyl]-8-oxo-, 1-[[(cyclohexyloxy)carbonyl]oxy]ethyl ester, dihydrochloride, (6R,7R)-
  • 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-[[(2-amino-4-thiazolyl)acetyl]amino]-3-[[[1-[2-(dimethylamino)ethyl]-1H-tetrazol-5-yl]thio]methyl]-8-oxo-, 1-[[(cyclohexyloxy)carbonyl]oxy]ethyl ester, dihydrochloride, [6R-(6α,7β)]-
  • 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-[[2-(2-aMino-4-thiazolyl)acetyl]aMino]-3-[[[1-[2-(diMethylaMino)ethyl]-1H-tetrazol-5-yl]thio]Methyl]-8-oxo-, 1-[[(cyclohexyloxy)carbonyl]oxy]ethyl ester, hydrochloride (1:2), (6R,7R)-
  • SCE 2174
  • 1-cyclohexyloxycarbonyloxyethyl (6R,7R)-7-[[2-(2-amino-1,3-thiazol-4-yl)acetyl]amino]-3-[[1-(2-dimethylaminoethyl)tetrazol-5-yl]sulfanylmethyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate dihydrochloride
  • (6R-(6-alpha,7-beta))-7-(((2-Amino-4-thiazolyl)acetyl)amino)-3-(((1-(2-(dimethylamino)ethyl)-1H-tetrazol-5-yl)thio)methyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid 1-(((cyclohexyloxy)carbonyl)oxy)ethyl ester dihydrochloride
  • Cefotiam (mixture of Diastereomers)
  • Cefotiam Hexetil 2HCl
CAS:
95789-30-3
MF:
C27H38ClN9O7S3
MW:
732.29
EINECS:
680-797-5
Product Categories:
  • Chiral Reagents
  • Heterocycles
  • Intermediates & Fine Chemicals
  • Pharmaceuticals
  • Sulfur & Selenium Compounds
Mol File:
95789-30-3.mol
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SCE 2174 Chemical Properties

Melting point:
120-130°C
storage temp. 
Hygroscopic, -20°C Freezer, Under Inert Atmosphere
solubility 
DMSO (Slightly), Methanol (Slightly)
form 
Solid
color 
White to Pale Yellow
CAS DataBase Reference
95789-30-3
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Safety Information

Toxicity
LD50 in male, female mice, male, female rats (mg/kg): 1290, 1150, 1470, 1620 i.p.; >2000 s.c.; >5000 orally (Chiba)
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SCE 2174 Usage And Synthesis

Description

Cefotiam hexetil hydrochloride is an orally active, broad-spectrum cephalosporin useful in the treatment of bacterial infections. It is a prodrug hydrolyzed in the GI tract and absorbed as cefotiam. Cefotiam hexetil hydrochloride is reported to be especially potent against Streptococci strains.

Chemical Properties

Off-White to Pale Yellow Solid

Originator

Takeda (Japan)

Uses

A semi-synthetic cephalosporin antibiotic. Antibacterial.

Definition

ChEBI: The dihydrochloride salt of cefotiam 1-(cyclohexyloxycarbonyloxy)ethyl ester. It is used as a prodrug for cefotiam.

brand name

Pansporin T

SCE 2174Supplier

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