1H-Pyrrolo[2,3-c]pyridine,7-methoxy-(9CI) Chemical Properties

Melting point:

110-114℃

Boiling point:

304℃

Density 

1.244

Flash point:

105℃

storage temp. 

Sealed in dry,Room Temperature

form 

powder

pka

14.15±0.40(Predicted)

color 

Yellow

InChI

InChI=1S/C8H8N2O/c1-11-8-7-6(2-4-9-7)3-5-10-8/h2-5,9H,1H3

InChIKey

RHEGHTSBMVYYAM-UHFFFAOYSA-N

SMILES

C1(OC)=NC=CC2C=CNC1=2

Safety Information

Hazard Codes 

Xn

Risk Statements 

22-37/38-41

Safety Statements 

26-39

WGK Germany 

3

HS Code 

2933998090

1H-Pyrrolo[2,3-c]pyridine,7-methoxy-(9CI) Usage And Synthesis

Synthesis

Step 2: (0648) To a solution of 2-(2-methoxy-3-nitropyridin-4-yl)-N,N-dimethylethylamine (5.9 g, 26 mmol) prepared in Step 1 in ethanol (275 mL) was added 10% palladium carbon (Degussa type, 1.5 g). The reaction mixture was placed under hydrogen atmosphere (15 psi) and shaken for 15 min. Upon completion of the reaction, the reaction mixture was filtered through a bed of diatomaceous earth and washed with dichloromethane (DCM). The filtrate was concentrated under reduced pressure to afford 7-methoxy-1H-pyrrolo[2,3-c]pyridine (4.3 g, 61% yield).

References

[1] Journal of Organic Chemistry, 2001, vol. 66, # 17, p. 5723 - 5730
[2] Patent: US2015/307465, 2015, A1. Location in patent: Paragraph 0648

1H-Pyrrolo[2,3-c]pyridine,7-methoxy-(9CI)(160590-40-9)Related Product Information

• Indole
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• 1H-Pyrrolo[2,3-c]pyridine,7-methoxy-(9CI)
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• 4,7-DIMETHOXY-1H-PYRROLO[2,3-C]PYRIDINE