ChemicalBook > Product Catalog > API > Antineoplastic agents > Natural sources of antineoplastic > epothilone E
epothilone E
epothilone E Basic information
- Product Name:
- epothilone E
- Synonyms:
-
- epothilone E
- [4S,7R,8S,9S,13R,14S,16S(E)]-13,14-Epoxy-4,8-dihydroxy-5,5,7,9-tetramethyl-16-[2-[2-(hydroxymethyl)thiazol-4-yl]-1-methylvinyl]-1-oxacyclohexadecane-2,6-dione
- (1R,5S,6S,7R,10S,14S,16S)-6,10-dihydroxy-14-[(E)-1-[2-(hydroxymethyl)-1,3-thiazol-4-yl]prop-1-en-2-yl]-5,7,9,9-tetramethyl-13,17-dioxabicyclo[14.1.0]heptadecane-8,12-dione
- 4,17-Dioxabicyclo[14.1.0]heptadecane-5,9-dione, 7,11-dihydroxy-3-[(1E)-2-[2-(hydroxymethyl)-4-thiazolyl]-1-methylethenyl]-8,8,10,12-tetramethyl-, (1S,3S,7S,10R,11S,12S,16R)-
- epothilone E USP/EP/BP
- CAS:
- 201049-37-8
- MF:
- C26H39NO7S
- MW:
- 509.66
- Mol File:
- 201049-37-8.mol
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epothilone E Chemical Properties
- Boiling point:
- 715.5±60.0 °C(Predicted)
- Density
- 1.187±0.06 g/cm3(Predicted)
- pka
- 13.15±0.10(Predicted)
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epothilone E Usage And Synthesis
Uses
Epothilone E is a related compound of Epothilones, which are a novel class of antineoplastic agents with antitubulin activity. In addition, Epothilones utilize a similar mechanism of action to that of taxanes and are less susceptible to multidrug resistance caused by P-glycoprotein. Studies showed that Epothilones exhibit antitumor activity against human cancer cells that are taxane-resistant.
epothilone ESupplier
Accendatech Co., LTD.
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- 13132578992
- sales@accendatech.com
Shanghai Witofly Chemical Co.,Ltd
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- sales@witofly.com
Zhengzhou Acme Chemical Co., Ltd.
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- 0371-0371-55629727 13323845623
- 2885676761@qq.com
Hubei widely chemical technology Co., Ltd.
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- 027-83991130 18627774460
- 1718093273@QQ.COM
Shanghai Linka Biotechnology Co., Ltd.
- Tel
- 15901858719
- 2126935757@qq.com