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9-OXO-11ALPHA,15S-DIHYDROXY-PROSTA-5Z,13E,17Z-TRIEN-1-OIC ACID

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9-OXO-11ALPHA,15S-DIHYDROXY-PROSTA-5Z,13E,17Z-TRIEN-1-OIC ACID Basic information

Product Name:
9-OXO-11ALPHA,15S-DIHYDROXY-PROSTA-5Z,13E,17Z-TRIEN-1-OIC ACID
Synonyms:
  • 9-OXO-11ALPHA,15S-DIHYDROXY-PROSTA-5Z,13E,17Z-TRIEN-1-OIC ACID
  • PROSTAGLANDIN E3
  • (5Z,11a,13E,15S,17Z) 11,15-dihydroxy-9-oxo-prosta-5,13,17-trien-1-oic acid
  • (5Z,13E,15S,17Z)-11α,15-Dihydroxy-9-oxoprosta-5,13,17-trien-1-oic acid
  • PGE3
  • Prostaglandin E3 Exclusive
  • Prosta-5,13,17-trien-1-oic acid, 11,15-dihydroxy-9-oxo-, (5Z,11α,13E,15S,17Z)-
  • Prosta-5,13,17-trien-1-oicacid, 11,15-dihydroxy-9-oxo-, (5Z,11a,13E,15S,17Z)-
CAS:
802-31-3
MF:
C20H30O5
MW:
350.45
Mol File:
802-31-3.mol
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9-OXO-11ALPHA,15S-DIHYDROXY-PROSTA-5Z,13E,17Z-TRIEN-1-OIC ACID Chemical Properties

Melting point:
84.5-85.5 °C
Boiling point:
541.0±50.0 °C(Predicted)
Density 
1.166±0.06 g/cm3(Predicted)
storage temp. 
Store at -20°C
solubility 
DMF: >100 mg/ml (from PGE2); DMSO: >100 mg/ml (from PGE2); Ethanol: >100 mg/ml (from PGE2); PBS pH 7.2: >5 mg/ml (from PGE2)
pka
4.75±0.10(Predicted)
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9-OXO-11ALPHA,15S-DIHYDROXY-PROSTA-5Z,13E,17Z-TRIEN-1-OIC ACID Usage And Synthesis

Uses

Prostaglandin E3 (PGE3) is formed via the cyclooxygenase (COX) metabolism of eicosapentaenoic acid. In human ocular tissue, it comprises 2.4% of the COX products formed. When applied to the eyes of a rabbit, a 1 μg dose of PGE3 decreases intraocular pressure from 21 mmHg to about 17 mmHg.

Definition

ChEBI: Prostaglandin E3 is a prostaglandins E. It has a role as a human metabolite. It is a conjugate acid of a prostaglandin E3(1-).

9-OXO-11ALPHA,15S-DIHYDROXY-PROSTA-5Z,13E,17Z-TRIEN-1-OIC ACIDSupplier

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9-OXO-11ALPHA,15S-DIHYDROXY-PROSTA-5Z,13E,17Z-TRIEN-1-OIC ACID(802-31-3)Related Product Information