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ergosterol-5,8-peroxide

Basic information Safety Supplier Related

ergosterol-5,8-peroxide Basic information

Product Name:
ergosterol-5,8-peroxide
Synonyms:
  • Ergosterol peroxide
  • (22E)-5α,8α-Epidioxy-5α-ergosta-6,22-dien-3β-ol
  • (22E)-5α,8α-Epidioxyergosta-6,22-diene-3β-ol
  • Ergosterol 5α,8α-epidioxide
  • Ergosterol endoperoxide
  • Peroxyergosterol
  • ergosterol-5,8-peroxide
  • Ergosta-6,22-dien-3-ol,5,8-epidioxy-, (3b,5a,8a,22E)-
CAS:
2061-64-5
MF:
C28H44O3
MW:
428.65
Product Categories:
  • Steroids
Mol File:
2061-64-5.mol
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ergosterol-5,8-peroxide Chemical Properties

Melting point:
178 °C
Boiling point:
499.7±45.0 °C(Predicted)
Density 
1.08±0.1 g/cm3(Predicted)
storage temp. 
Store at -20°C
solubility 
Methanol: soluble
form 
Powder
pka
14.97±0.70(Predicted)
color 
White to off-white
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ergosterol-5,8-peroxide Usage And Synthesis

Uses

Network pharmacology and molecular docking study on inhibition of Mpro, primary protease of COVID-19, by Poria cocos and its active compounds.

Definition

ChEBI: Ergosterol peroxide is an ergostanoid that is ergosta-6,22-dien-3-ol with a peroxy group between positions 5 and 8 (the 3beta,5alpha,8alpha,22E stereoisomer). Isolated from Ganoderma lucidum and Cordyceps sinensis, it exhibits antimycobacterial, trypanocidal and antineoplastic activities. It has a role as a metabolite, an antineoplastic agent, an antimycobacterial drug and a trypanocidal drug. It is an organic peroxide, an ergostanoid, a 3beta-sterol and a member of phytosterols. It is functionally related to an ergosterol.

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