nimbolide
nimbolide Basic information
- Product Name:
- nimbolide
- Synonyms:
-
- nimbolide
- (17R)-7α,15β:21,23-Diepoxy-6α-hydroxy-4,8-dimethyl-1-oxo-11-methoxycarbonyl-18,24-dinor-11,12-seco-5α-chola-2,13,20,22-tetrene-4α-carboxylic acid γ-lactone
- NSC 309909
- 2H,5H-Cyclopenta[d']naphtho[1,8-bc:2,3-b']difuran-6-acetic acid, 8-(3-furanyl)-2a,5a,6,6a,8,9,9a,10a,10b,10c-decahydro-2a,5a,6a,7-tetramethyl-2,5-dioxo-, methyl ester, (2aR,5aR,6S,6aR,8R,9aR,10aS,10bR,10cR)-
- methyl [(2aR,5aR,6S,6aR,8R,9aR,10aS,10bR,10cR)-8-furan-3-yl-2a,5a,6a,7-tetramethyl-2,5-dioxo-2a,5a,6,6a,8,9,9a,10a,10b,10c-decahydro-2H,5H-cyclopenta[d]naphtho[2,3-b:1,8-b''c'']difuran-6-yl]acetate
- Nimbolide (25 mg)
- Nimbolide, CyclinA and ERK1/2 inhibitor
- CAS:
- 25990-37-8
- MF:
- C27H30O7
- MW:
- 466.52
- Product Categories:
-
- Heterocycles
- Intermediates & Fine Chemicals
- Pharmaceuticals
- Mol File:
- 25990-37-8.mol
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nimbolide Chemical Properties
- Melting point:
- >223°C (dec.)
- Boiling point:
- 608.6±55.0 °C(Predicted)
- Density
- 1.32±0.1 g/cm3(Predicted)
- storage temp.
- Hygroscopic, -20°C Freezer, Under Inert Atmosphere
- solubility
- Chloroform, Ethyl Acetate
- form
- powder
- color
- Light Beige to Yellow
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nimbolide Usage And Synthesis
Chemical Properties
Light Beige Solid
Uses
Nimbolide, a natural triterpenoid present in the edible parts of the neem tree (Azadirachta indica), was found to be growth-inhibitory in human colon carcinoma HT-29 cells. Nimbolide treatment of cells at 2.5 - 10 μM resulted in moderate to very strong growth inhibition.
storage
Store at -20°C
nimbolideSupplier
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