trinactin
trinactin Basic information
- Product Name:
- trinactin
- Synonyms:
-
- 5,14,23-Tridemethyl-5,14,23-triethylnonactin
- AKD-1D, S 3466B
- Akd 1D
- Akd1D
- Akd-1D
- 4,13,22,31,37,38,39,40-Octaoxapentacyclo[32.2.1.17,10.116,19.125,28]tetracontane-3,12,21,30-tetrone, 5,14,23-triethyl-2,11,20,29,32-pentamethyl-, (1R,2R,5R,7R,10S,11S,14S,16S,19R,20R,23R,25R,28S,29S,32S,34S)-
- (1r,2r,5r,7r,10s,11s,14s,16s,19r,20r,23r,25r,28s,29s,32s,34s)-5,14,23-triethyl-2,11,20,29,32-pentamethyl-4,13,22,31,37,38,39,40-octaoxapentacyclo[32.2.1.17,10.116,19.125,28]tetracontane-3,12,21,30-tetrone
- CAS:
- 7561-71-9
- MF:
- C43H70O12
- MW:
- 779.01
- Mol File:
- 7561-71-9.mol
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trinactin Chemical Properties
- Melting point:
- 67-68 °C
- Boiling point:
- 909.7±65.0 °C(Predicted)
- Density
- 1.024±0.06 g/cm3(Predicted)
- storage temp.
- Store at -20°C
- solubility
- DMF: soluble; DMSO: soluble; Ethanol: soluble; Methanol: soluble
- form
- Colorless film.
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trinactin Usage And Synthesis
Uses
Trinactin is a member of the macrotetrolide complex produced by a range of Streptomyces sp.. Early literature reported that trinactin is a monovalent cation ionophore with high selectivity for ammonium and potassium. Trinactin inhibits T-cell proliferation induced by IL-2, and cytokine production at nanomolar levels for IL-2, IL-4, IL-5 and interferon-γ. Trinactin has not previously been available for intensive investigation.
Uses
Trinactin is a hydrophobic cyclic ester that acts as a macrotetrolide antibiotic.
trinactinSupplier
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